VPS41 and RILP

Data Source:
BioGRID (pull down)

		VPS41	RILP
Description		VPS41 subunit of HOPS complex	Rab interacting lysosomal protein
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Cytosol Phagocytic Vesicle Membrane Late Endosome Membrane Protein-containing Complex Ciliary Basal Body
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport	Endosome To Lysosome Transport Regulation Of Multivesicular Body Size Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Catabolic Process Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Cilium Assembly Intralumenal Vesicle Formation
Pathways			MHC class II antigen presentation
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)
Interacting Genes		12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B	12 interacting genes: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS11 VPS16 VPS18 VPS36 VPS39 VPS41
Entrez ID		27072	83547
HPRD ID		10402	09706
Ensembl ID		ENSG00000006715	ENSG00000167705
Uniprot IDs		P49754	Q96NA2
PDB IDs			1YHN
Enriched GO Terms of Interacting Partners?
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