ANKRD1 and MYBPC1

Data Source:
BioGRID (two hybrid)

		ANKRD1	MYBPC1
Description		ankyrin repeat domain 1	myosin binding protein C1
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol I Band	Cytosol Myofibril Myosin Filament
	Molecular Function	RNA Polymerase II Transcription Factor Binding P53 Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Titin Binding Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding R-SMAD Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Myosin Binding Titin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Regulation Of Lipid Metabolic Process Cellular Response To Drug Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Secretion Cardiac Muscle Tissue Morphogenesis Protein Kinase C Signaling Cellular Response To Lipopolysaccharide Cellular Response To Mechanical Stimulus Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound Cellular Response To Hypoxia Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of DNA Biosynthetic Process	Cell Adhesion Muscle Filament Sliding
Pathways		PPARA activates gene expression	Striated Muscle Contraction
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Intraocular pressure ( 29617998) Refractive error ( 32231278)	Blood protein levels ( 28240269) Lung function (FEV1) ( 24023788) Memory decline ( 31985465)
Interacting Genes		23 interacting genes: APPL1 ARHGDIB ASH2L CASQ2 CDCA7L DNAJB6 DST DYSF LRPPRC MAPRE3 MEOX2 MYBPC1 MYL1 MYOM2 MYPN NAGK REPS1 SPANXN2 TRIM55 TRIM63 TTN TULP3 ZNF446	23 interacting genes: ACO1 AMOT ANKRD1 ASH2L C1QTNF9 CALM1 CAPN3 CLIP4 DNAJB5 DNAJB6 DYSF FHL1 FHL2 FHL3 KLHL41 MEOX2 MYBPC2 NCF1 RAF1 SGCG TRIM55 TRIM63 TTN
Entrez ID		27063	4604
HPRD ID		10647	01185
Ensembl ID		ENSG00000148677	ENSG00000196091
Uniprot IDs		A0A384NYH5 Q15327	A8KAB1 B3KPP3 Q00872 Q86TA8
PDB IDs			1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM
Enriched GO Terms of Interacting Partners?
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