NOX1 and NOXO1

Data Source:
BioGRID (pull down)

		NOX1	NOXO1
Description		NADPH oxidase 1	NADPH oxidase organizer 1
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Plasma Membrane Cell Junction NADPH Oxidase Complex	Cytoplasm Plasma Membrane NADPH Oxidase Complex
	Molecular Function	Voltage-gated Ion Channel Activity Protein Binding Superoxide-generating NAD(P)H Oxidase Activity Small GTPase Binding Metal Ion Binding NADP Binding	Protein Binding Phospholipid Binding Superoxide-generating NADPH Oxidase Activator Activity Enzyme Binding Molecular Adaptor Activity
	Biological Process	Angiogenesis Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin NADP Metabolic Process Defense Response Inflammatory Response Signal Transduction Regulation Of Blood Pressure Positive Regulation Of Cell Population Proliferation Positive Regulation Of Vascular Endothelial Growth Factor Production Cell Migration Extracellular Matrix Organization Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Superoxide Anion Generation Hydrogen Peroxide Metabolic Process Positive Regulation Of Integrin Biosynthetic Process Respiratory Burst Positive Regulation Of JNK Cascade Positive Regulation Of Smooth Muscle Cell Proliferation Intracellular PH Elevation Cellular Response To Hyperoxia Oxygen Metabolic Process Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Stress Response To Acidic PH	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Extracellular Matrix Disassembly Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping	RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping
Drugs		Oxygen	Ecabet
Diseases
GWAS			Red cell distribution width ( 32888494)
Interacting Genes		5 interacting genes: ARHGEF7 CYBA NOXA1 NOXO1 TBXA2R	2 interacting genes: NOX1 NOXA1
Entrez ID		27035	124056
HPRD ID		02203	14834
Ensembl ID		ENSG00000007952	ENSG00000196408
Uniprot IDs		A6NGA6 Q1ZYL4 Q9Y5S8	A8K832 Q8NFA2
PDB IDs			2L73
Enriched GO Terms of Interacting Partners?
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