DNAI1 and ZIC3

Data Source:
BioGRID (two hybrid)

		DNAI1	ZIC3
Description		dynein axonemal intermediate chain 1	Zic family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Microtubule Cilium Outer Dynein Arm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Motor Activity Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cilium Movement Microtubule-based Movement Determination Of Left/right Symmetry Flagellated Sperm Motility Outer Dynein Arm Assembly	Heart Looping Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Central Nervous System Development Anterior/posterior Pattern Specification Cell Differentiation Lung Development Somatic Stem Cell Population Maintenance Determination Of Pancreatic Left/right Asymmetry Determination Of Left/right Asymmetry In Nervous System Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Determination Of Digestive Tract Left/right Asymmetry Determination Of Liver Left/right Asymmetry
Pathways			POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells
Drugs
Diseases		Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome	Heterotaxy; Situs ambiguus
GWAS		Anti-drug antibodies in autoimmune disease (time to event) ( 33125391)	Refractive error ( 32231278)
Interacting Genes		2 interacting genes: PAFAH1B1 SQSTM1	5 interacting genes: CTNNB1 GLI3 SRF TP53 TWIST1
Entrez ID		27019	7547
HPRD ID		05080	02225
Ensembl ID		ENSG00000122735	ENSG00000156925
Uniprot IDs		A0A087WWV9 A0A140VJI0 Q9UI46	O60481
PDB IDs			2EJ4 2RPC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?