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DNAI1 and PAFAH1B1
Data Source:
HPRD
(in vivo)
DNAI1
PAFAH1B1
Description
dynein axonemal intermediate chain 1
platelet activating factor acetylhydrolase 1b regulatory subunit 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoskeleton
Microtubule
Cilium
Outer Dynein Arm
Astral Microtubule
Kinetochore
Nuclear Envelope
Centrosome
Cytosol
Microtubule Associated Complex
Cytoplasmic Microtubule
Cell Cortex
1-alkyl-2-acetylglycerophosphocholine Esterase Complex
Cell Leading Edge
Motile Cilium
Nuclear Membrane
Neuron Projection
Neuronal Cell Body
Synapse
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Axon Cytoplasm
Molecular Function
Motor Activity
Protein Binding
Dynein Light Chain Binding
Dynein Heavy Chain Binding
Protein Binding
Microtubule Binding
Heparin Binding
Dynactin Binding
Identical Protein Binding
Phospholipase Binding
Protein Heterodimerization Activity
Microtubule Plus-end Binding
Phosphoprotein Binding
Dynein Complex Binding
Biological Process
Cilium Movement
Microtubule-based Movement
Determination Of Left/right Symmetry
Flagellated Sperm Motility
Outer Dynein Arm Assembly
G2/M Transition Of Mitotic Cell Cycle
Establishment Of Mitotic Spindle Orientation
Microtubule Cytoskeleton Organization
Acrosome Assembly
Neuron Migration
Microtubule-based Process
Nuclear Migration
Chemical Synaptic Transmission
Germ Cell Development
Neuroblast Proliferation
Learning Or Memory
Retrograde Axonal Transport
Adult Locomotory Behavior
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Lipid Catabolic Process
Transmission Of Nerve Impulse
Corpus Callosum Morphogenesis
Hippocampus Development
Layer Formation In Cerebral Cortex
Cerebral Cortex Development
Actin Cytoskeleton Organization
Microtubule Organizing Center Organization
Reelin-mediated Signaling Pathway
Platelet Activating Factor Metabolic Process
Vesicle Transport Along Microtubule
Brain Morphogenesis
Neuromuscular Process Controlling Balance
Microtubule Sliding
Cell Division
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Microtubule Motor Activity
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
AURKA Activation by TPX2
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Anti-drug antibodies in autoimmune disease (time to event) (
33125391
)
Adverse response to drug (
30420678
)
Mean platelet volume (
32888494
)
Neurociticism (
29500382
)
Neuroticism (
27089181
)
Self-reported tiredness (
28194004
)
Interacting Genes
2 interacting genes:
PAFAH1B1
SQSTM1
22 interacting genes:
CLIP1
CSNK2A1
DAB1
DCTN1
DCTN2
DCX
DNAI1
FBXO7
HSPH1
KARS1
KATNA1
KATNB1
MAP1B
MAP2
NDE1
NDEL1
NUDC
PAFAH1B2
PAFAH1B3
PDE4D
TNIK
TUBA1A
Entrez ID
27019
5048
HPRD ID
05080
03329
Ensembl ID
ENSG00000122735
ENSG00000007168
Uniprot IDs
A0A087WWV9
A0A140VJI0
Q9UI46
A0A6Q8PFT2
A0A6Q8PFU3
P43034
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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