BLOC1S1 and FBXO44

Data Source:
BioGRID (two hybrid)

		BLOC1S1	FBXO44
Description		biogenesis of lysosomal organelles complex 1 subunit 1	F-box protein 44
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex BORC Complex Axon Cytoplasm	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Anterograde Axonal Transport Aerobic Respiration Endosomal Transport Peptidyl-lysine Acetylation Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization	Protein Polyubiquitination Glycoprotein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		18 interacting genes: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 DCTN2 FBXO44 HGS MAGEB4 MTA1 NOTCH1 PBX2 PELP1 PTN SNAPC5 SNAPIN USHBP1	12 interacting genes: BLOC1S1 BORCS6 BRCA1 C11orf45 HSF2BP ISY1-RAB43 MEOX2 PRDM5 SERTAD3 SKP1 SPG21 UBC
Entrez ID		2647	93611
HPRD ID		03263	16445
Ensembl ID		ENSG00000135441	ENSG00000132879
Uniprot IDs		P78537	A0A024R4F9 A0A024R4J6 B7Z1P2 Q9H4M3
PDB IDs			3WSO 5B4N
Enriched GO Terms of Interacting Partners?
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