BLOC1S6 and CCDC22

Data Source:
BioGRID (two hybrid)

		BLOC1S6	CCDC22
Description		biogenesis of lysosomal organelles complex 1 subunit 6	coiled-coil domain containing 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex Presynapse Axon Cytoplasm	Cellular_component Nucleoplasm Endosome Cytosol
	Molecular Function	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding	Protein Binding Cullin Family Protein Binding
	Biological Process	Anterograde Axonal Transport Synaptic Vesicle Docking Neuron Projection Development Melanosome Transport Melanosome Organization Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation	Cellular Copper Ion Homeostasis Golgi To Plasma Membrane Transport Cytoplasmic Sequestering Of NF-kappaB Protein Transport Protein Ubiquitination Endocytic Recycling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Retrograde Transport, Endosome To Plasma Membrane Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways		Golgi Associated Vesicle Biogenesis	Neddylation
Drugs
Diseases
GWAS			Vitiligo ( 27723757)
Interacting Genes		49 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 C4orf46 CCDC136 CCDC22 CCHCR1 CCR2 CDK5R1 CEP44 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 INSYN1 KRT13 KRT72 LURAP1 MED21 MLPH NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 RINT1 SKA1 SLC4A1 SMN1 SMN2 SNAPIN STX11 STX12 STX1A SYCE3 TPM1 TPM3 TRAK1 WASHC3	8 interacting genes: ACTG1 ARSA BLOC1S6 CPNE1 CPNE4 KRT27 OIP5 USHBP1
Entrez ID		26258	28952
HPRD ID		16055	06594
Ensembl ID		ENSG00000104164	ENSG00000101997
Uniprot IDs		B3KY40 H3BST1 Q9UL45	A0A024QZ03 O60826
PDB IDs
Enriched GO Terms of Interacting Partners?
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