PHF19 and YTHDC1

Data Source:
BioGRID (two hybrid)

		PHF19	YTHDC1
Description		PHD finger protein 19	YTH domain containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm ESC/E(Z) Complex	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding N6-methyladenosine-containing RNA Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Histone H3-K27 Methylation	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome
Pathways		PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 31043758 27680694) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 28135244 27618448) Refractive error ( 32231278)	Mean corpuscular hemoglobin ( 32888494) Obesity-related traits ( 23251661)
Interacting Genes		21 interacting genes: BAG4 CSNK2A1 DVL3 H3C1 HOMEZ HOXB5 INO80E KDM1A LZTS2 PICK1 POTEB3 RCOR3 SNIP1 SUV39H1 SUV39H2 THAP1 THAP7 TSPYL2 YTHDC1 ZNF837 ZRANB1	42 interacting genes: ABL1 ADAMTS4 ANKRD28 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 KRTAP10-6 LAMC3 LAMTOR5 LZTS2 MPRIP PHF19 PICK1 PLG PROSER2 RBMY1A1 RBMY1F RBMY1J RNPS1 SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51
Entrez ID		26147	91746
HPRD ID		17846	11689
Ensembl ID		ENSG00000119403	ENSG00000083896
Uniprot IDs		A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3	J3QR07 Q96MU7
PDB IDs		2E5Q 4BD3 6NQ3 6WAU	2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7 6SYZ 6SZ1 6SZ2 6SZ3 6SZL 6SZN 6SZR 6SZT 6SZX 6SZY 6T01 6T02 6T03 6T04 6T05 6T06 6T07 6T08 6T09 6T0A 6T0C 6T0D 6T0O 6T0X 6T0Z 6T10 6T11 6T12 6WE8 6WE9 6WEA 6YKE 6YKI 6YKJ 6YKZ 6YL0 6YL8 6YL9 6YNI 6YNJ 6YNK 6YNL 6YNM 6YNN 6YNO 6YNP 6YOQ 6ZCM 6ZCN 6ZD9
Enriched GO Terms of Interacting Partners?
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