ERC2 and BSN

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		ERC2	BSN
Description		ELKS/RAB6-interacting/CAST family member 2	bassoon presynaptic cytomatrix protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Growth Cone Presynaptic Membrane Presynaptic Active Zone Cytoskeleton Of Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse GABA-ergic Synapse	Nucleus Synaptic Vesicle Cell Surface Postsynaptic Density Axon Dendrite Synaptic Vesicle Membrane Neuron Projection Terminus Presynaptic Active Zone Cytoskeleton Of Presynaptic Active Zone Excitatory Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding Structural Constituent Of Presynaptic Active Zone	Metal Ion Binding Structural Constituent Of Presynaptic Active Zone
	Biological Process	Neuromuscular Synaptic Transmission Synaptic Vesicle Priming Regulation Of Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure	Chemical Synaptic Transmission Protein Localization To Synapse Maintenance Of Presynaptic Active Zone Structure Regulation Of Synaptic Vesicle Cycle Presynapse To Nucleus Signaling Pathway Presynaptic Active Zone Assembly
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Adult body size ( 32376654) Alcohol dependence ( 24166409) Bipolar disorder and schizophrenia ( 21057379) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 26955885) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549 28869591) Hip bone size ( 31053729) Hip geometry ( 17903296) Intertrochanteric region size ( 31053729) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Morning vs. evening chronotype ( 26955885 27494321) Night sleep phenotypes ( 27126917) Periodontitis (Mean PAL) ( 24024966) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Sense of smell ( 26632684) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tourette syndrome ( 30818990) Trochanter size ( 31053729)	Blood protein levels ( 29875488 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399) Childhood ear infection ( 27182965 28928442) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Cognitive function ( 25644384) Coronary artery disease ( 33020668) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908 17554300 21102463) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Gut microbiota (functional units) ( 27694959) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Household income (MTAG) ( 31844048) Immature fraction of reticulocytes ( 32888494 27863252) Inflammatory bowel disease ( 28067908 23128233) Intelligence (MTAG) ( 29326435) Mean spheric corpuscular volume ( 32888494) Mood instability ( 31168069) Morning person ( 30696823) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Reticulocyte count ( 32888494) Self-rated health ( 27864402) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827 21297633)
Interacting Genes		8 interacting genes: BSN MYB PCLO PPFIA1 PPFIA2 PPFIA3 PPFIA4 RIMS1	1 interacting genes: ERC2
Entrez ID		26059	8927
HPRD ID		10810	04933
Ensembl ID		ENSG00000187672	ENSG00000164061
Uniprot IDs		O15083	Q9UPA5
PDB IDs
Enriched GO Terms of Interacting Partners?
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