NGDN and AATF

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		NGDN	AATF
Description		neuroguidin	apoptosis antagonizing transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleoplasm Nucleolus Mitochondrion Filopodium Axon Dendrite Small-subunit Processome	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Golgi Apparatus
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Protein Kinase Binding Leucine Zipper Domain Binding Tau Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Translation	Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Embryonic Cleavage Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway
Pathways			NRAGE signals death through JNK
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Body mass index ( 26426971) Erectile dysfunction ( 30583798) Obesity-related traits ( 23251661) Thyroid volume in Hashimotoâ€™s thyroiditis ( 32019955)
Interacting Genes		5 interacting genes: AATF CSNK2B MFAP1 NOM1 SRPK2	28 interacting genes: ATM ATR AURKA CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 FBXO7 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 NEDD4L NGDN PALS2 PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468
Entrez ID		25983	26574
HPRD ID		10708	12236
Ensembl ID		ENSG00000129460	ENSG00000275700
Uniprot IDs		Q8NEJ9	Q9NY61
PDB IDs			5W6A
Enriched GO Terms of Interacting Partners?
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