CHMP2B and MALSU1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP2B	MALSU1
Description		charged multivesicular body protein 2B	mitochondrial assembly of ribosomal large subunit 1
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GO Annotations	Cellular Component	ESCRT III Complex Cytoplasm Lysosome Endosome Late Endosome Multivesicular Body Cytosol Plasma Membrane Late Endosome Membrane Extracellular Exosome	Mitochondrion Mitochondrial Large Ribosomal Subunit Cytosol
	Molecular Function	Protein Binding Protein Domain Specific Binding Cadherin Binding	Protein Binding Ribosomal Large Subunit Binding
	Biological Process	Autophagy Nucleus Organization Endosome Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Cognition Multivesicular Body-lysosome Fusion Midbody Abscission Neuron Cellular Homeostasis Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell ESCRT III Complex Disassembly	Negative Regulation Of Translation Ribosomal Large Subunit Biogenesis Negative Regulation Of Mitochondrial Translation Negative Regulation Of Ribosome Biogenesis
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases		Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
GWAS		Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Iron status biomarkers (transferrin saturation) ( 28334935)
Interacting Genes		12 interacting genes: ATP5F1C CENPF CHMP3 DPY30 FBXO7 MALSU1 PHGDH PNMA1 TERF2IP TRAF2 USP54 USP8	13 interacting genes: CHMP2B DCTD INCA1 LMO3 MEOX2 MYBPHL NTAQ1 PLEKHG4 SP6 TRIM55 TRIM63 ZFP90 ZNF426
Entrez ID		25978	115416
HPRD ID		13174	12918
Ensembl ID		ENSG00000083937	ENSG00000156928
Uniprot IDs		B2RE76 Q9UQN3	Q96EH3
PDB IDs		2JQK	5OOL 5OOM
Enriched GO Terms of Interacting Partners?
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