GEMIN5 and DDX20

Data Source:
HPRD (in vitro, in vivo)

		GEMIN5	DDX20
Description		gem nuclear organelle associated protein 5	DEAD-box helicase 20
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Gemin2 Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding SnRNA Binding U1 SnRNA Binding U4 SnRNA Binding U4atac SnRNA Binding Ribosome Binding	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding Repressing Transcription Factor Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Translation Regulation Of Translation Import Into Nucleus Protein-containing Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Positive Regulation Of Apoptotic Process Import Into Nucleus
Pathways		snRNP Assembly	snRNP Assembly
Drugs
Diseases
GWAS		Venous thromboembolism ( 32232851)	Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)
Interacting Genes		21 interacting genes: CLK1 DDX20 EIF4E GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNU1-1 RNU2-1 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3 SUMO2	32 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53
Entrez ID		25929	11218
HPRD ID		06109	05859
Ensembl ID		ENSG00000082516	ENSG00000064703
Uniprot IDs		B7ZLC9 Q58EZ8 Q8TEQ6	Q9H4N4 Q9UHI6
PDB IDs		5GXH 5GXI 5H1J 5H1K 5H1L 5H1M 5H3S 5H3T 5H3U 5TEE 5TEF 5THA 6RNQ 6RNS	2OXC 3B7G
Enriched GO Terms of Interacting Partners?
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