BRMS1 and BRMS1L

Data Source:
HPRD (in vivo)

		BRMS1	BRMS1L
Description		BRMS1 transcriptional repressor and anoikis regulator	BRMS1 like transcriptional repressor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Sin3-type Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Negative Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Regulation Of Growth
Pathways		HDACs deacetylate histones Potential therapeutics for SARS
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)
Interacting Genes		49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	22 interacting genes: ACTN2 AMOTL2 BRMS1 CEP70 CYTOR DEUP1 EXOC5 HDAC1 HDAC2 ING1 MCRS1 MID2 PBX1 PBX2 RBBP4 RBBP7 RBP1 SAP30 SIN3A TEX11 TULP3 TXLNA
Entrez ID		25855	84312
HPRD ID		05879	16564
Ensembl ID		ENSG00000174744	ENSG00000100916
Uniprot IDs		G5E9I4 Q9HCU9	Q5PSV4
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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