LCE5A and SLC39A7

Data Source:
BioGRID (two hybrid)

		LCE5A	SLC39A7
Description		late cornified envelope 5A	solute carrier family 39 member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Keratinization	Cellular Zinc Ion Homeostasis Zinc Ion Transmembrane Transport
Pathways		Formation of the cornified envelope	Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic march ( 26542096) Hair morphology ( 19896111) Inflammatory skin disease ( 25574825)
Interacting Genes		66 interacting genes: ADAM12 ALPP CHIC2 CHRD CREB5 CYP21A2 CYSRT1 FBLN1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP12-4 KRTAP21-2 KRTAP3-1 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2B LCE2C LCE4A NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUTF2 PLAC8 PLSCR2 PLSCR3 PLSCR4 POU4F2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRED2 SPRY1 TRIM42 UBE2I VWC2L ZNF655	29 interacting genes: AQP6 BIK CLCA4 CRCT1 ERCC6 GJA8 KCNF1 KRTAP1-3 KRTAP5-7 KRTAP9-2 LCE1A LCE1C LCE1F LCE2C LCE2D LCE4A LCE5A LELP1 RGS17 RSPO2 SHISAL1 SLC34A2 SMCP SPRY3 TMEM14B TNFRSF10D UNC93A WFDC12 YY1
Entrez ID		254910	7922
HPRD ID		17265	09028
Ensembl ID		ENSG00000186207	ENSG00000112473
Uniprot IDs		Q5TCM9	A0A024RCX7 B4DZZ8 Q92504
PDB IDs
Enriched GO Terms of Interacting Partners?
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