G6PD and LINC01554

Data Source:
BioGRID (unspecified method)

		G6PD	LINC01554
Description		glucose-6-phosphate dehydrogenase	long intergenic non-protein coding RNA 1554
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Membrane Centriolar Satellite Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Glucose-6-phosphate Dehydrogenase Activity Protein Binding Glucose Binding Identical Protein Binding Protein Homodimerization Activity NADP Binding
	Biological Process	Glucose Metabolic Process Pentose-phosphate Shunt Lipid Metabolic Process Cholesterol Biosynthetic Process NADP Metabolic Process NADPH Regeneration Glutathione Metabolic Process Pentose-phosphate Shunt, Oxidative Branch Response To Iron(III) Ion Negative Regulation Of Protein Glutathionylation Response To Organic Cyclic Compound Pentose Biosynthetic Process Substantia Nigra Development Response To Food Cellular Response To Oxidative Stress Erythrocyte Maturation Regulation Of Neuron Apoptotic Process Response To Ethanol Ribose Phosphate Biosynthetic Process Glucose 6-phosphate Metabolic Process Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		TP53 Regulates Metabolic Genes Pentose phosphate pathway
Drugs		Glycolic acid Nicotinamide adenine dinucleotide phosphate 16-Bromoepiandrosterone Artenimol
Diseases		Anemia due to disorders of glutathione metabolism, including: Glucose-6-phosphate dehydrogenase (G6PD) deficiency; Glutathione peroxidase (GPX) deficiency; Gamma-glutamylcysteine synthetase (GCLC) deficiency; Glutathione synthetase (GSS) deficiency Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Bilirubin levels ( 19419973) Glycated hemoglobin levels ( 31213470 28898252) Hemoglobin levels ( 26366553) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin ( 28453575) Mean corpuscular volume ( 28453575) Red blood cell count ( 28453575) Red blood cell traits ( 23446634 23696099) Red cell distribution width ( 28453575)
Interacting Genes		4 interacting genes: CDC42 LINC01554 PAK4 SUMO4	141 interacting genes: AARS1 ACADVL ACIN1 ACTB ACTG1 ACTN1 ACTN3 ACTR3 ALDOA ANXA2 ANXA5 ANXA6 APEX1 ARHGAP1 ASS1 ATAD3A ATIC ATP5F1A BZW2 CANX CCT2 CCT3 CCT4 CCT6A CCT7 CKAP4 CS CTPS1 DDX3X DDX46 DHX9 DNAH2 DNAJA1 DST DYNC1H1 EDARADD EEF1G EEF2 EIF3A EIF3E EIF4A2 EIF4B ENO1 ENO3 EPRS1 ERO1A G3BP1 G6PD GANAB GAPDH GARS1 GDI2 GPI GTF2I HIVEP2 HMCN1 HNRNPF HSP90AA1 HSP90B1 HSPA1L HSPA5 HSPA8 HSPA9 HSPD1 HYOU1 IDH1 IPO4 IPO7 IPO9 ITPR2 KARS1 KPNA1 KPNB1 KRT18 KRT7 KRT8 KRT8P3 LRPPRC MCM7 MSN MYO18A NAP1L1 NAP1L4 NCBP1 NCL NPM1 OLA1 OXCT1 PABPC1 PCBP2 PDIA3 PDIA6 PFAS PGD PGK1 PGM1 PHGDH PKM PLOD2 PMPCA POR PPP2R1A PSMC1 PSMD2 PSMD7 PTBP1 RDX RPL6 RPSA RTCB RTN4 SARS1 SEPTIN7 SEPTIN9 SERPINH1 SFPQ SQSTM1 TARS1 TGFBI THOP1 TKT TTF2 TUBA1A TUBA8 TUBB TUBB2A TUBB3 TUBB4A TUBB4B TUBB6 TUFM TXNRD1 TYMP UBA1 VCL VCP VIM VPS35 WARS1 XPO1 XRCC5
Entrez ID		2539	202299
HPRD ID		02377	16896
Ensembl ID		ENSG00000160211	ENSG00000236882
Uniprot IDs		A0A384NL00 P11413
PDB IDs		1QKI 2BH9 2BHL 5UKW 6E07 6E08 6JYU
Enriched GO Terms of Interacting Partners?
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