FUCA2 and LCE1B

Data Source:
BioGRID (two hybrid)

		FUCA2	LCE1B
Description		alpha-L-fucosidase 2	late cornified envelope 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Alpha-L-fucosidase Activity Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Fucose Metabolic Process Response To Bacterium Glycoside Catabolic Process Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Entry Of Bacterium Into Host Cell	Keratinization
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation	Formation of the cornified envelope
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		18 interacting genes: GPR37 GPRC5B GUCD1 HOXA1 KRTAP10-1 KRTAP4-12 KRTAP5-2 KRTAP5-3 LCE1A LCE1B LCE1E LCE4A MEOX2 NUFIP2 PIN1 TNPO2 VWC2 WNT11	72 interacting genes: ADAMTSL4 BEND5 CYSRT1 FBLN1 FUCA2 HOXA1 KRT31 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A LCE5A MDFI MEOX2 NAPSA NBPF19 NOTCH2NLA NUFIP2 OTX1 P4HB RGS17 RGS20 RNF4 SMCP SPRY1 SPRY2 SPRY3 TGM1 TRIM42
Entrez ID		2519	353132
HPRD ID		00649	17259
Ensembl ID		ENSG00000001036	ENSG00000196734
Uniprot IDs		Q9BTY2	Q5T7P3
PDB IDs
Enriched GO Terms of Interacting Partners?
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