PRKD3 and NUDT3

Data Source:
BioGRID (two hybrid)

		PRKD3	NUDT3
Description		protein kinase D3	nudix hydrolase 3
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Membrane	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity
	Biological Process	Protein Phosphorylation Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Sphingolipid Biosynthetic Process Protein Kinase D Signaling	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process
Pathways		Sphingolipid de novo biosynthesis	Synthesis of pyrophosphates in the cytosol
Drugs
Diseases
GWAS		Body mass index ( 28892062) Chronic lymphocytic leukemia ( 28165464 24292274) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Pulse pressure ( 27841878) Schizophrenia ( 23974872) Systolic blood pressure ( 28135244 27841878)	Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29381148 20935630) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412) Myeloproliferative neoplasms ( 33057200) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: BCL6 DLAT GSK3A IKBKG KPNA2 KPNB1 MYH3 NUDT3 POLL SKA2 TAF1 VAMP2	36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		23683	11165
HPRD ID		06151	14849
Ensembl ID		ENSG00000115825	ENSG00000272325
Uniprot IDs		O94806	O95989
PDB IDs		2D9Z	2FVV 2Q9P 6PCK 6PCL
Enriched GO Terms of Interacting Partners?
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