KPNA6 and ANP32A

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KPNA6	ANP32A
Description		karyopherin subunit alpha 6	acidic nuclear phosphoprotein 32 family member A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Host Cell	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	RNA Binding Protein Binding Histone Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Viral Genome Replication Mitigation Of Host Defenses By Symbiont Positive Regulation Of Transcription By RNA Polymerase II Maternal Process Involved In Female Pregnancy Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Viral Life Cycle	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Stability
Pathways			HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Esophageal cancer ( 21642993)
Interacting Genes		37 interacting genes: ANKRD11 ANP32A ANP32B ARNT BRCA1 CDKN1B CREBBP CSE1L DCPS EPAS1 FAM90A1 FRG1BP GEMIN2 HIF1A IL1A JRK KAT5 KEAP1 KPNB1 LMNA LMNB1 MAGED1 NMNAT1 NOP2 NUP50 POLR3C POM121 POU6F2 RAC1 RELB RNMT SKP2 SMARCB1 STAT1 STAT3 TAF9 ZNF131	29 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		23633	8125
HPRD ID		09465	09014
Ensembl ID		ENSG00000025800	ENSG00000140350
Uniprot IDs		O60684	A0A384P5U2 P39687
PDB IDs		4UAD	2JE0 2JE1 4XOS
Enriched GO Terms of Interacting Partners?
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