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LPAR3 and GNAI2
Data Source:
HPRD
(in vivo)
LPAR3
GNAI2
Description
lysophosphatidic acid receptor 3
G protein subunit alpha i2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Axon
Synapse
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Heterotrimeric G-protein Complex
Plasma Membrane
Membrane
Dendrite
Midbody
Cell Body
Membrane Raft
Synapse
Extracellular Exosome
Extracellular Vesicle
Molecular Function
G-protein Alpha-subunit Binding
G Protein-coupled Receptor Activity
Protein Binding
Phospholipid Binding
Lipid Binding
Lysophosphatidic Acid Receptor Activity
G Protein-coupled Receptor Binding
GTPase Activity
Protein Binding
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
Metal Ion Binding
Biological Process
Activation Of MAPK Activity
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Chemical Synaptic Transmission
Regulation Of Metabolic Process
Bleb Assembly
Positive Regulation Of Collateral Sprouting
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Positive Regulation Of Calcium Ion Transport
G Protein-coupled Adenosine Receptor Signaling Pathway
Protein Folding
Cell Cycle
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Gamma-aminobutyric Acid Signaling Pathway
Response To Nutrient
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Migration
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of NAD(P)H Oxidase Activity
Positive Regulation Of Urine Volume
Positive Regulation Of Renal Sodium Excretion
Negative Regulation Of Calcium Ion-dependent Exocytosis
Positive Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of Synaptic Transmission
Cell Division
Regulation Of Calcium Ion Transport
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Negative Regulation Of Protein Tyrosine Phosphatase Activity
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Neural Precursor Cell Proliferation
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
G alpha (q) signalling events
G alpha (i) signalling events
Lysosphingolipid and LPA receptors
PLC beta mediated events
PLC beta mediated events
Adenylate cyclase inhibitory pathway
Adenylate cyclase inhibitory pathway
G-protein activation
ADP signalling through P2Y purinoceptor 12
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
Regulation of insulin secretion
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
Adrenal carcinoma
GWAS
Cerebrospinal fluid t-tau:AB1-42 ratio (
28641921
)
Dental caries (
23064961
)
Glucose homeostasis traits (
25524916
)
Heel bone mineral density (
30598549
)
Urinary albumin-to-creatinine ratio in non-diabetics (
26631737
)
Body mass index (
26426971
)
Body size at age 10 (
32376654
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Lymphocyte counts (
32888494
)
Lymphocyte percentage of white cells (
32888494
)
Monocyte count (
32888494
)
Morning person (
30696823
)
Sleep duration (short sleep) (
30846698
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
58 interacting genes:
APP
AQP6
ARL13B
ASZ1
BCL2L13
C16orf54
CD53
CD74
CD79A
CLDN2
CLDN7
CLDN9
CLEC12B
CPLX4
CREB3L1
CYB561
CYBRD1
EDA
ERGIC3
FAM209A
FAM210B
FFAR2
FNDC9
GJB5
GNAI2
GORAB
GPX8
JAGN1
KCNC1
KCNJ6
LEPROTL1
LHFPL5
LIME1
LMNA
MFF
MGST3
MRM1
MS4A4A
NDUFAF2
OPRM1
PGRMC2
RELL2
RETREG3
SCN3B
SGMS2
SHISAL1
SLC10A6
SLC16A2
SLC35C2
TFEC
THAP4
TMEM14B
TMEM237
TMEM31
TMEM41A
TMEM52B
TMEM70
TMEM79
64 interacting genes:
ADCY1
ADORA1
ADRA2A
ADRA2B
ADRB2
AGTR2
C5AR1
CAV1
CCR5
CHRM1
CNR1
CXCL8
CXCR1
CXCR2
DRD2
EDNRA
EGFR
EYA1
EYA2
F2R
FPR1
GNB2
GNB4
GPSM2
GPSM3
IGF1R
ITCH
KRT31
KRT40
KRTAP10-8
LHB
LHCGR
LPAR3
LTB4R
MDFI
MRGPRX1
MTNR1A
MTNR1B
NGB
NOTCH2NLA
NPM1
NUCB1
OPRD1
OPRM1
P2RY12
PCP2
PLSCR1
PTEN
PTPRU
RASD1
RGS12
RGS14
RGS16
RGS18
RGS19
RGS20
RGS4
RGS5
RIC8A
TBXA2R
TRIP6
TSHR
TTC1
TUBA4A
Entrez ID
23566
2771
HPRD ID
05486
00764
Ensembl ID
ENSG00000171517
ENSG00000114353
Uniprot IDs
Q9UBY5
B3KP24
B3KX51
P04899
PDB IDs
6D9H
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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