WBP1 and WWP1

Data Source:
HPRD (in vivo, in vitro)

		WBP1	WWP1
Description		WW domain binding protein 1	WW domain containing E3 ubiquitin protein ligase 1
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GO Annotations	Cellular Component	Cellular_component	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding WW Domain Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Biological_process	Protein Polyubiquitination Signal Transduction Central Nervous System Development Protein Ubiquitination Ion Transmembrane Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell
Pathways			Downregulation of ERBB4 signaling Stimuli-sensing channels Regulation of RUNX2 expression and activity Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31152163)
Interacting Genes		10 interacting genes: CACNA1A COPA EPN2 MAGI1 NEDD4 SMCO4 WWP1 WWP2 YAP1 ZMYND10	55 interacting genes: ARRDC1 ARRDC2 ARRDC3 ASH2L ATN1 CLCN5 CPSF6 DAG1 DAZAP2 DIDO1 EWSR1 FAM189A2 FBXL18 HSPB1 IKBKG IL2RG IL6R KLF2 KLF5 LAPTM5 LATS1 LNX1 LZTR1 MACROH2A2 MIR19A MIR19B1 NFE2 NOTCH1 PCBD1 PHF20L1 PRKAA2 PYGM RASA1 RNF11 RTN4 RUNX1 SCNN1A SFTPC SMAD3 SMAD5 STAT6 TFAP2A TGIF1 TP53BP2 TRAF4 UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 WASL WBP1 WBP2 YWHAQ ZNF638
Entrez ID		23559	11059
HPRD ID		09510	03811
Ensembl ID		ENSG00000239779	ENSG00000123124
Uniprot IDs		A0A384P602 Q96G27	Q9H0M0
PDB IDs		1JMQ 1K5R	1ND7 2OP7 5HPS 5HPT 6J1X 6J1Y
Enriched GO Terms of Interacting Partners?
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