TSPAN12 and RNF152

Data Source:
BioGRID (two hybrid)

		TSPAN12	RNF152
Description		tetraspanin 12	ring finger protein 152
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane	Lysosome Lysosomal Membrane Integral Component Of Organelle Membrane
	Molecular Function	Protein Binding Wnt-activated Receptor Activity	Ubiquitin-protein Transferase Activity Protein Binding Small GTPase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Angiogenesis Cell Surface Receptor Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Regulation Of Angiogenesis Regulation Of Vascular Endothelial Growth Factor Signaling Pathway	Apoptotic Process Positive Regulation Of Autophagy Protein Ubiquitination Cellular Response To Amino Acid Starvation Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of TORC1 Signaling
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases		Familial exudative vitreoretinopathy (FEVR), including: Exudative vitreoretinopathy 1 (EVR1); Exudative vitreoretinopathy2, X-linked (EVR2); Exudative vitreoretinopathy 4 (EVR4); Exudative vitreoretinopathy 5 (EVR5); Norrie disease (ND)
GWAS		Bitter alcoholic beverage consumption ( 31046077) Heel bone mineral density ( 30598549)	Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372 26831199)
Interacting Genes		21 interacting genes: CDS2 CTXN3 CXCL16 CYBC1 EMP3 GPR25 GPR37L1 IGFBP5 MARCHF2 MGST3 NINJ2 PMP22 RFT1 RNF152 STX8 TEX264 TFCP2 TMEM140 TMEM147 TMEM182 TMEM218	10 interacting genes: CROCC EBP GJA8 KIR2DL3 RHEB RRAGA TSPAN12 UBE2E1 UBE2N UBE2W
Entrez ID		23554	220441
HPRD ID		15509	11514
Ensembl ID		ENSG00000106025	ENSG00000176641
Uniprot IDs		A0A024R740 O95859	Q8N8N0
PDB IDs
Enriched GO Terms of Interacting Partners?
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