PIP5K1C and HDHD2

Data Source:
HPRD (two hybrid)

		PIP5K1C	HDHD2
Description		phosphatidylinositol-4-phosphate 5-kinase type 1 gamma	haloacid dehalogenase like hydrolase domain containing 2
Image
GO Annotations	Cellular Component	Phagocytic Cup Uropod Nucleoplasm Cytosol Adherens Junction Focal Adhesion Endosome Membrane Ruffle Membrane Presynapse	Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity	Protein Binding Phosphatase Activity Enzyme Binding Metal Ion Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Phagocytosis Regulation Of Phosphatidylinositol 3-kinase Signaling Synaptic Vesicle Exocytosis Actin Cytoskeleton Organization Neutrophil Chemotaxis Adherens Junction Assembly Phosphatidylinositol Phosphorylation Synaptic Vesicle Endocytosis Membrane Organization Clathrin-dependent Endocytosis Cell-cell Adhesion	Biological_process Dephosphorylation
Pathways		Synthesis of PIPs at the plasma membrane SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Clathrin-mediated endocytosis
Drugs
Diseases		Lethal congenital contractural syndrome (LCCS)
GWAS			Blood protein levels ( 30072576 29875488) Fruit consumption ( 32066663)
Interacting Genes		17 interacting genes: AKT1 AKT2 AP1B1 AP2B1 ARF6 BTK CDH1 CDK5 HDHD2 ITGB1 LAPTM4B LRP2 NEDD4 PKD1 SMURF1 SRC TLN2	12 interacting genes: ADGRB2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11
Entrez ID		23396	84064
HPRD ID		05834	13640
Ensembl ID		ENSG00000186111	ENSG00000167220
Uniprot IDs		O60331	Q9H0R4 V9HW73
PDB IDs		2G35 3H1Z 3H85	3HLT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?