TNS2 and OBSL1

Data Source:
BioGRID (two hybrid)

		TNS2	OBSL1
Description		tensin 2	obscurin like cytoskeletal adaptor 1
Image
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion	Cytoplasm Golgi Apparatus Centrosome Cytosol Intercalated Disc Z Disc M Band Synapse Perinuclear Region Of Cytoplasm 3M Complex
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Kinase Binding Identical Protein Binding Metal Ion Binding	Protein Binding Cytoskeletal Anchor Activity
	Biological Process	Kidney Development Negative Regulation Of Cell Population Proliferation Response To Muscle Activity Cellular Homeostasis Collagen Metabolic Process Multicellular Organism Growth Peptidyl-tyrosine Dephosphorylation Intracellular Signal Transduction Negative Regulation Of Insulin Receptor Signaling Pathway Multicellular Organismal Homeostasis	Microtubule Cytoskeleton Organization Cytoskeleton Organization Golgi Organization Regulation Of Mitotic Nuclear Division Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Retina Layer Formation Protein Localization To Golgi Apparatus Post-translational Protein Modification Positive Regulation Of Dendrite Morphogenesis Cardiac Myofibril Assembly
Pathways			Neddylation
Drugs
Diseases			3M syndrome
GWAS
Interacting Genes		150 interacting genes: ADCK5 AMMECR1 AP1S2 AQP1 ARID5A ASB3 AXL BAHD1 BLZF1 BRCA1 C11orf87 C1orf94 CATSPER1 CCDC33 CNNM3 COX6B2 CPSF7 CRX CSNK1E CTSZ DCAF11 DCAF8 DDIT4L DLC1 DOK3 DZIP1 DZIP3 EGFR ENKD1 EPB41L4A EPDR1 EPS8L2 ERBB2 ERBB3 ERBB4 FABP7 FAM114A1 FAM228A FASLG FGF21 FGFR1 FOXO1 GATA1 GBA3 GFI1B HOXA1 HOXB9 HOXC8 HUWE1 ID2 IHO1 INO80B ITGB3 ITGB5 ITGB7 KCTD9 KIF1A KIT KPRP KRT76 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP13-1 KRTAP13-2 KRTAP23-1 KRTAP3-1 KRTAP4-4 KRTAP6-3 LASP1 LPXN LUZP4 MET MGAT5B MPEG1 MT2A MTDH MYBPHL MYH7B MYPOP NBPF19 NMU NOTCH2NLA NT5C NUBP2 OBSL1 OTX1 PATZ1 PER1 PHF1 PIN1 PKP1 PLB1 PLK3 PLSCR3 POLR1H POLR3F PRR22 RAMAC RBAK RBPMS REEP6 REL RFT1 RNF6 SDCCAG8 SERTAD2 SH2B3 SHFL SOCS7 SORBS3 SPATA12 SPRY2 SPRY4 SUSD2 SUV39H1 TBC1D16 TCP10L TEKT3 TEKT5 TENT5A TENT5B TFAP2D TLE5 TM4SF19 TRIM8 TSC1 TWSG1 USP54 WAC WDFY3 ZCCHC14 ZIM2 ZNF134 ZNF205 ZNF250 ZNF417 ZNF497 ZNF575 ZNF586 ZNF587 ZNF648 ZNF655 ZNF688 ZNF837	5 interacting genes: HSPB1 KCNE4 LTB4R2 MCPH1 TNS2
Entrez ID		23371	23363
HPRD ID		16256	19306
Ensembl ID		ENSG00000111077	ENSG00000124006
Uniprot IDs		A0A024RB48 Q63HR2	O75147 Q9H8B3
PDB IDs		2DKQ 2KNO 2L6K 2LOZ 3HQC	2CPC 2E6P 2E6Q 2LU7 2LVC 2WP3 2WWK 2WWM 3KNB 5FM5
Enriched GO Terms of Interacting Partners?
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