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FMR1 and RBM14
Data Source:
BioGRID
(two hybrid)
FMR1
RBM14
Description
FMRP translational regulator 1
RNA binding motif protein 14
Image
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Cytoplasm
Cytosol
Polysome
MRNA Cap Binding Complex
Chromocenter
Cytoplasmic Stress Granule
Postsynaptic Density
Cajal Body
Membrane
Extrinsic Component Of Plasma Membrane
Axon
Dendrite
Growth Cone
Filopodium Tip
SMN Complex
Cytoplasmic Ribonucleoprotein Granule
Presynaptic Membrane
Polysomal Ribosome
Cell Projection
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Perikaryon
Axon Terminus
Dendritic Spine Neck
Synapse
Postsynaptic Membrane
Perinuclear Region Of Cytoplasm
Neuronal Ribonucleoprotein Granule
Glial Cell Projection
Presynapse
Postsynapse
Dendritic Filopodium
Messenger Ribonucleoprotein Complex
Growth Cone Filopodium
Ribonucleoprotein Complex
Nucleus
Nucleoplasm
Transcription Regulator Complex
Nucleolus
Cytoplasm
Nuclear Speck
Ribonucleoprotein Complex
Molecular Function
G-quadruplex RNA Binding
Chromatin Binding
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Microtubule Binding
Poly(U) RNA Binding
Translation Repressor Activity
Translation Initiation Factor Binding
RNA Strand Annealing Activity
Poly(G) Binding
Methylated Histone Binding
SiRNA Binding
MiRNA Binding
RNA Stem-loop Binding
Identical Protein Binding
Protein Homodimerization Activity
Ribosome Binding
Ion Channel Binding
Translation Regulator Activity
Protein Heterodimerization Activity
MRNA 5'-UTR Binding
Dynein Complex Binding
Sequence-specific MRNA Binding
RNA Binding
MRNA Binding
Protein Binding
Nuclear Receptor Coactivator Activity
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Receptor Internalization
MRNA Processing
Cellular Response To DNA Damage Stimulus
Glutamate Receptor Signaling Pathway
Nervous System Development
RNA Splicing
Viral Process
Negative Regulation Of Translation
Gene Silencing By RNA
Positive Regulation Of Histone Phosphorylation
Cellular Response To UV
Regulation Of MRNA Stability
Modulation By Host Of Viral RNA Genome Replication
Positive Regulation Of Translation
Negative Regulation Of Translational Initiation
Regulation Of Neurotransmitter Secretion
MRNA Transport
Regulation Of Filopodium Assembly
Positive Regulation Of Filopodium Assembly
Regulation Of Gene Silencing By MiRNA
Regulation Of Dendritic Spine Development
Positive Regulation Of Dendritic Spine Development
Cellular Response To Hydroxyurea
Cellular Response To Virus
Regulation Of Neuronal Action Potential
Negative Regulation Of Long-term Synaptic Depression
Positive Regulation Of Intracellular Transport Of Viral Material
Negative Regulation Of Voltage-gated Calcium Channel Activity
Positive Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of MRNA Catabolic Process
Positive Regulation Of MRNA Binding
Negative Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Gene Silencing By MiRNA
Negative Regulation Of Cytoplasmic Translation
Positive Regulation Of Response To DNA Damage Stimulus
MRNA Splicing, Via Spliceosome
Activation Of Innate Immune Response
Response To Hormone
Histone Deacetylation
Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Centriole Replication
SMAD Protein Signal Transduction
Centriole Assembly
Pathways
RUNX2 regulates bone development
Drugs
Diseases
Premature ovarian failure
Fragile X Syndrome, including: Fragile X Syndrome (FXS); Fragile X tremor/ataxia syndrome (FXTAS)
GWAS
Antineutrophil cytoplasmic antibody-associated vasculitis (
22808956
)
Fragile X syndrome (
30531935
)
Bipolar disorder (
21926972
)
Interacting Genes
27 interacting genes:
AKAP9
ATG5
CASK
CWC25
CYFIP1
CYFIP2
EFHC1
FSD2
FXR1
FXR2
INCA1
LIMS1
MEOX1
NCL
NUFIP1
NUFIP2
POLR1C
RANBP9
RBM14
SF3B2
SPAG5
STAU1
SUOX
UBE2I
WBP2NL
YBX1
ZBTB42
113 interacting genes:
AKAP9
ATN1
CASK
CEP55
CRLF3
CTBP1
DDX17
DDX6
DMRTB1
DYNLT1
EP300
FMR1
FXR2
HNRNPK
HOMER3
KHDRBS2
KIFAP3
KLC4
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NCOA6
NDEL1
NFKBID
NR3C1
PARD6G
PARP1
PCBP1
PRKCI
QKI
RBM10
RBM5
RPA2
RUNX1
RUNX2
SLAIN1
SS18
SYT1
TARBP2
TRIM55
TRIM63
UBE2I
XRCC5
YWHAE
Entrez ID
2332
10432
HPRD ID
02398
11485
Ensembl ID
ENSG00000102081
ENSG00000239306
Uniprot IDs
Q06787
A0A0S2Z4Z0
A0A0S2Z567
A0A0S2Z5V2
Q96PK6
PDB IDs
2BKD
2FMR
2LA5
2QND
4OVA
4QVZ
4QW2
5DE5
5DE8
5DEA
5UWJ
5UWO
2DNP
Enriched GO Terms of Interacting Partners
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