TUT4 and CYP27B1

Data Source:
BioGRID (affinity chromatography technology)

		TUT4	CYP27B1
Description		terminal uridylyl transferase 4	cytochrome P450 family 27 subfamily B member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleolus Cytoplasm Cytosol Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Outer Membrane
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Nucleotidyltransferase Activity MiRNA Binding RNA Uridylyltransferase Activity	Calcidiol 1-monooxygenase Activity Iron Ion Binding Heme Binding Secalciferol 1-monooxygenase Activity
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Oocyte Maturation Negative Regulation Of Transposition, RNA-mediated MiRNA Metabolic Process MiRNA Catabolic Process Stem Cell Population Maintenance Pre-miRNA Processing RNA 3'-end Processing Histone MRNA Catabolic Process RNA 3' Uridylation Polyuridylation-dependent MRNA Catabolic Process	Vitamin Metabolic Process Calcium Ion Transport Negative Regulation Of Cell Population Proliferation Negative Regulation Of Calcidiol 1-monooxygenase Activity Positive Regulation Of Vitamin D 24-hydroxylase Activity Bone Mineralization Negative Regulation Of Cell Growth Regulation Of Bone Mineralization Response To Lipopolysaccharide Response To Vitamin D Response To Interferon-gamma Calcitriol Biosynthetic Process From Calciol Vitamin D Metabolic Process Vitamin D Catabolic Process Response To Estrogen Positive Regulation Of Keratinocyte Differentiation Decidualization Calcium Ion Homeostasis G1 To G0 Transition Positive Regulation Of Vitamin D Receptor Signaling Pathway
Pathways		Deadenylation of mRNA	Vitamin D (calciferol) metabolism Vitamins Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)
Drugs			Alfacalcidol
Diseases			Type I diabetes mellitus
GWAS			Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 19525955 21833088)
Interacting Genes		10 interacting genes: MIR143 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		23318	1594
HPRD ID		15700	02031
Ensembl ID		ENSG00000134744	ENSG00000111012
Uniprot IDs		A0A0C4DFM7 Q5TAX3	O15528
PDB IDs		6IW6
Enriched GO Terms of Interacting Partners?
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