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ANKRD28 and NOTCH3
Data Source:
BioGRID
(two hybrid)
ANKRD28
NOTCH3
Description
ankyrin repeat domain 28
notch receptor 3
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Nucleoplasm
Cytosol
Golgi Membrane
Extracellular Region
Nucleoplasm
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Cell Surface
Actin Cytoskeleton
Integral Component Of Membrane
Receptor Complex
Molecular Function
Protein Binding
Calcium Ion Binding
Protein Binding
Signaling Receptor Activity
Identical Protein Binding
Cadherin Binding
Biological Process
COPII Vesicle Coating
Transcription Initiation From RNA Polymerase II Promoter
Notch Signaling Pathway
Positive Regulation Of Transcription Of Notch Receptor Target
Axon Guidance
Negative Regulation Of Notch Signaling Pathway
Regulation Of Developmental Process
Pathways
Telomere Extension By Telomerase
COPII-mediated vesicle transport
Pre-NOTCH Processing in the Endoplasmic Reticulum
Pre-NOTCH Transcription and Translation
Pre-NOTCH Processing in Golgi
Pre-NOTCH Processing in Golgi
Notch-HLH transcription pathway
Defective LFNG causes SCDO3
NOTCH3 Activation and Transmission of Signal to the Nucleus
NOTCH3 Activation and Transmission of Signal to the Nucleus
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
Noncanonical activation of NOTCH3
Drugs
Diseases
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Mean platelet volume (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
Refractive error (
32231278
)
Pulse pressure (
27841878
30578418
)
Toxoplasma gondii sag1 antibody levels (
33204752
)
Interacting Genes
35 interacting genes:
ABCF2
AGPAT2
ANK2
ANKFY1
ANKRD26
ANKRD50
BCL3
BRCA1
CCDC187
CD164
CSNK2B
EEF1G
EHMT2
EIF3D
GADD45GIP1
HNRNPK
HNRNPR
INCA1
KCNV2
MYOM1
NOTCH2
NOTCH3
PIBF1
PTRH1
RNF11
TGM2
TGS1
THAP7
TMIE
TNKS
TNKS2
TTN
UACA
YTHDC1
ZNF512B
48 interacting genes:
ANKRD28
BAG2
BTF3L4
C1QL1
C8orf76
CBFA2T2
CHUK
CNTD1
CPNE6
CRIP2
CSNK2B
DLL1
EGFL7
FBLN1
GGT6
JAG1
JAG2
KAT2B
LINC00839
MAML1
MAML2
MAML3
MPPED2
MTDH
MYC
NEDD9
PPIA
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSEN1
PSEN2
RBPJ
RET
RMI2
SCGB3A1
SLC39A1
SNW1
SNX19
SORBS3
SPTLC2
TMEM108
TNNT2
TPT1
WDR25
XKR8
Entrez ID
23243
4854
HPRD ID
10651
02607
Ensembl ID
ENSG00000206560
ENSG00000074181
Uniprot IDs
A0A024R2I9
O15084
Q9UM47
PDB IDs
4ZLP
5CZV
5CZX
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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