TTLL12 and FAM222B

Data Source:
BioGRID (two hybrid)

		TTLL12	FAM222B
Description		tubulin tyrosine ligase like 12	family with sequence similarity 222 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Spindle Midbody	Nucleoplasm
	Molecular Function	Tubulin-tyrosine Ligase Activity Protein Binding ATP Binding Tubulin Binding Histone-lysine N-methyltransferase Activity H4K20me3 Modified Histone Binding	Protein Binding
	Biological Process	Regulation Of Mitotic Cell Cycle Protein Phosphopantetheinylation Histone Lysine Methylation Innate Immune Response Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Histone H4-K20 Methylation
Pathways		Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Molar-incisor hypomineralization ( 23918034) Monocyte count ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494)	Estimated glomerular filtration rate reduction (30%) ( 30955190) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Red blood cell count ( 32888494) Red cell distribution width ( 27863252)
Interacting Genes		7 interacting genes: CSNK2A2 DNAJB1 EEF1A1 EEF1A2 FAM222B PRR35 SUMO2	35 interacting genes: ANKRD10 BAG4 BANP BPIFA1 C10orf55 C19orf54 CDCA4 CNFN FAM168B FHL3 FOSB HYI INTS11 KRTAP11-1 KRTAP26-1 KRTAP3-1 LRRC61 OIP5 PDLIM4 PFDN5 PLA2G10 PRR20A PRR20B PRR20C PRR20D PRR20E RUNX1 SOHLH1 TRIP6 TSC1 TTLL12 UBQLN2 UFSP1 WWOX ZMYND12
Entrez ID		23170	55731
HPRD ID		13782	07693
Ensembl ID		ENSG00000100304	ENSG00000173065
Uniprot IDs		A0A024R4U3 Q14166	A0A024QZ60 B3KQ88 B3KTH5 B4DRX9 Q8WU58
PDB IDs
Enriched GO Terms of Interacting Partners?
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