MAPK8IP3 and KLC2

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		MAPK8IP3	KLC2
Description		mitogen-activated protein kinase 8 interacting protein 3	kinesin light chain 2
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm Axon Cytoplasm	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex
	Molecular Function	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Signaling Receptor Complex Adaptor Activity	Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Activation Of JUN Kinase Activity Vesicle-mediated Transport Axon Regeneration Regulation Of JNK Cascade Axon Development Anterograde Axonal Protein Transport	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998)	Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)
Interacting Genes		26 interacting genes: ARL4D CASP3 KLC1 KLC2 LDLRAP1 MAP2K1 MAP2K4 MAP2K7 MAP3K11 MAP3K5 MAPK10 MAPK8 MAPK8IP1 MAPK8IP2 MAPK9 PTK2 RAD51 RAD51D RAF1 RIC8A SRC SULT4A1 TLR2 TLR4 TLR9 ZNF575	16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ
Entrez ID		23162	64837
HPRD ID		12014	13917
Ensembl ID		ENSG00000138834	ENSG00000174996
Uniprot IDs		A0A087WYG2 B7ZMF3 E9PFH7 Q9UPT6	Q9H0B6
PDB IDs		4PXJ	3CEQ 3EDT
Enriched GO Terms of Interacting Partners?
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