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IKZF3 and MORN3
Data Source:
BioGRID
(two hybrid)
IKZF3
MORN3
Description
IKAROS family zinc finger 3
MORN repeat containing 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nucleus
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Sequence-specific DNA Binding
Metal Ion Binding
Promoter-specific Chromatin Binding
Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Mesoderm Development
Response To Bacterium
Regulation Of B Cell Proliferation
B Cell Activation
Regulation Of Apoptotic Process
Regulation Of B Cell Differentiation
Regulation Of Lymphocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Acute lymphoblastic leukemia (childhood) (
29348612
)
Asthma (
31959851
31619474
28461288
)
Asthma (moderate or severe) (
30552067
)
Asthma and hay fever (
24388013
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Atopic march (
26542096
)
Bronchial hyperresponsiveness in asthma (
27439200
)
Crohn's disease (
28067908
21102463
)
Eosinophil counts (
32888494
27863252
)
Eosinophil percentage of granulocytes (
27863252
)
Eosinophil percentage of white cells (
32888494
27863252
)
Inflammatory bowel disease (
28067908
23128233
)
Lymphocyte counts (
29403010
32888494
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Marginal zone lymphoma or systemic lupus erythematosus (
31407831
)
Monocyte count (
32888494
)
Multiple sclerosis (
31604244
24076602
)
Neutrophil percentage of granulocytes (
27863252
)
Pediatric autoimmune diseases (
26301688
)
Polycystic ovary syndrome (
30343302
)
Primary biliary cholangitis (
19458352
23000144
20639880
26394269
28062665
30643196
)
Primary biliary cirrhosis (
22961000
)
Refractive error (
32231278
)
Rheumatoid arthritis (
30423114
23143596
24390342
20453842
)
Rheumatoid arthritis (ACPA-positive) (
23143596
24532676
)
Selective IgA deficiency (
27723758
)
Self-reported allergy (
23817569
)
Systemic lupus erythematosus (
27399966
26502338
)
Systemic lupus erythematosus and Systemic sclerosis (
23740937
)
Systemic sclerosis (
31672989
)
Type 1 diabetes (
30659077
25751624
)
Ulcerative colitis (
28067908
20228799
21297633
)
Interacting Genes
157 interacting genes:
ABLIM3
AKAP10
AKAP9
ANKS1A
AQP1
ARMC7
ARNT2
ATP6V0D1
ATP6V0D2
ATPAF2
ATXN7L2
BCAS2
BCL2L1
BLK
BLZF1
BYSL
C1orf109
C2CD6
CABP4
CABP5
CARD9
CATSPER1
CCDC102B
CCDC187
CCDC24
CCDC57
CCHCR1
CDC37
CDC7
CDK4
CDKN1A
CDKN2D
CFAP206
CHCHD2
CHD3
CKS1B
CLCNKA
CRBN
CRK
CRYBA4
DGCR6
DTX2
EFHC1
EGLN3
EMC2
ENKD1
EXOC8
EXOSC5
FAM124B
FANCG
FANCL
FARS2
FBF1
FHL3
FRS3
GEM
GOLGA2
GOLGA6A
GRAP2
GRB2
HNRNPF
HNRNPLL
HOXC8
HRAS
IKZF1
IKZF4
IKZF5
ING5
KANK2
KAT5
KIF9
KIFC3
KLHL38
KRT19
LDOC1
LENG1
LGALS14
LMO1
LMO2
LMO4
LNX1
LONRF1
MAD2L2
MAGOHB
MCM7
MCRS1
MID2
MISP
MKRN3
MORN3
MRPL28
MRPL53
MYO15B
NATD1
NEK6
NFKBID
NME7
NOS3
NTAQ1
NUDT16L1
NXT2
OAZ3
OSGIN1
PCID2
PDZD4
PFDN5
PIK3R1
PIK3R2
PIN1
POLM
POLR1C
PPP1R16B
PPP1R18
PRDM1
PRKAA1
PRKAA2
PRKAB2
PSMA1
PSMF1
RAD51D
RBBP8
RCOR3
RHOA
RNF6
RUNX1
SCNM1
SMARCB1
SMARCD1
SPG21
STAMBPL1
STK16
STK26
STX11
SUMO1
TBC1D22B
TCAF1
TCAP
TCEANC
TCHP
TEKT3
TEKT4
TFAP2D
TLE5
TRAPPC6A
TRIM42
TSEN15
TSGA10IP
TSSK3
TSTD2
UBE2I
USP2
VBP1
YES1
ZGPAT
ZMYM2
ZNF587
ZNF76
65 interacting genes:
ABHD11
ADAMTSL4
ARID5A
BEX2
C14orf119
CDCA7L
CTDSP1
DYNLL1
DYNLL2
EIF3D
ENKD1
FAM166B
FAM90A1
FANCL
FARS2
FTO
GEM
GLYCTK
GOLGA2
GPANK1
GUCD1
HOOK2
HOXB2
IKZF3
INO80B
KANK2
KLHL38
KRT15
LHX2
LZTS2
MAGEA6
MB21D2
MEOX2
MISP
MKRN3
MLH1
MYOZ3
NDUFAB1
NFU1
NOXA1
NTAQ1
OIP5
PAX6
PHF1
PICK1
POLR1C
PRKAA2
PRKAB2
PRR5L
RBPMS
RNF39
RSPH1
RUSC1
SCNM1
SH2D4A
SOX5
SUOX
TASOR2
TEKT4
TRAF1
TRAF2
TRIP13
YPEL3
ZNF438
ZNF76
Entrez ID
22806
283385
HPRD ID
05869
17330
Ensembl ID
ENSG00000161405
ENSG00000139714
Uniprot IDs
Q9UKT9
Q6PF18
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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