FCGR2B and MRTFB

Data Source:
BioGRID (affinity chromatography technology)

		FCGR2B	MRTFB
Description		Fc fragment of IgG receptor IIb	myocardin related transcription factor B
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Dendritic Spine Cell Body	Nucleus
	Molecular Function	Amyloid-beta Binding Transmembrane Signaling Receptor Activity Protein Binding Low-affinity IgG Receptor Activity IgG Binding Protein-containing Complex Binding	Transcription Coactivator Activity Protein Binding Cadherin Binding
	Biological Process	Negative Regulation Of Type I Hypersensitivity Negative Regulation Of Antibody-dependent Cellular Cytotoxicity Negative Regulation Of Cytokine Production Follicular Dendritic Cell Activation Mature B Cell Differentiation Involved In Immune Response Follicular B Cell Differentiation Immune Complex Clearance By Monocytes And Macrophages Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Regulation Of B Cell Antigen Processing And Presentation Negative Regulation Of Immunoglobulin Production Regulation Of Adaptive Immune Response Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Humoral Immune Response Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Receptor-mediated Endocytosis Phagocytosis, Engulfment Defense Response Inflammatory Response Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Response To Bacterium Regulation Of Signaling Receptor Activity Viral Process Immunoglobulin Mediated Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cerebellum Development Negative Regulation Of B Cell Proliferation Negative Regulation Of Interleukin-10 Production Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Negative Regulation Of Macrophage Activation Negative Regulation Of Cytotoxic T Cell Degranulation Regulation Of Innate Immune Response Mast Cell Activation Positive Regulation Of JNK Cascade Negative Regulation Of Phagocytosis Positive Regulation Of Phagocytosis Regulation Of Immune Response Negative Regulation Of Immune Response Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of B Cell Activation Cellular Response To Molecule Of Bacterial Origin Regulation Of Immune Complex Clearance By Monocytes And Macrophages Positive Regulation Of Neuron Death Negative Regulation Of Neutrophil Activation Regulation Of Dendritic Spine Maintenance Cellular Response To Amyloid-beta Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Dendritic Cell Differentiation	Muscle Organ Development Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II Smooth Muscle Cell Differentiation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Etanercept Human immunoglobulin G Abciximab Tositumomab Alemtuzumab Antithymocyte immunoglobulin (rabbit) Palivizumab Daclizumab Bevacizumab Sarilumab
Diseases		Systemic lupus erythematosus
GWAS		Apolipoprotein A1 levels ( 32203549) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Birth weight ( 31043758 27680694) Blood protein levels ( 30072576 29875488 28240269) Granulocyte count ( 27863252) HDL cholesterol levels ( 32203549) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) IgG levels ( 28628107) Inflammatory bowel disease ( 28067908 23128233) Lipid metabolism phenotypes ( 22286219) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Offspring birth weight ( 31043758) Red blood cell count ( 32888494) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Rheumatoid arthritis ( 30423114) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systemic lupus erythematosus ( 26502338) Ulcerative colitis ( 28067908 21297633) White blood cell count ( 32888494 27863252)
Interacting Genes		15 interacting genes: APCS BLK CRP ERG28 GAB1 GRB2 INPP5D INPPL1 LY6E LYN MAPK1 MAPK3 PRKCA PTPN11 PTPN6	7 interacting genes: KDM3A MRTFA NCOA3 SMAD1 SMAD7 SRF SVIL
Entrez ID		2213	57496
HPRD ID		06849	17577
Ensembl ID		ENSG00000072694	ENSG00000186260
Uniprot IDs		P31994	Q9ULH7
PDB IDs		2FCB 3WJJ 5OCC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?