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ETV4 and HOXD4
Data Source:
BioGRID
(two hybrid)
ETV4
HOXD4
Description
ETS variant transcription factor 4
homeobox D4
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Chromatin
Nucleus
Nucleoplasm
Cell Junction
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Cell Differentiation
Positive Regulation Of Keratinocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Multicellular Organism Development
Anterior/posterior Pattern Specification
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Skeletal System Morphogenesis
Pathways
MAPK6/MAPK4 signaling
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
Ewing's sarcoma
Prostate cancer
GWAS
Estimated glomerular filtration rate (
31015462
)
Male-pattern baldness (
28196072
)
Obstructive sleep apnea trait (apnea hypopnea index) (
29077507
)
Pelvic organ prolapse (moderate/severe) (
26545240
)
Interacting Genes
14 interacting genes:
APP
ATXN1
EP300
EPAS1
HIF1A
HOXD4
HTT
JUN
MEOX2
SAE1
SMAD4
SRF
STK11
UBA2
21 interacting genes:
ASB8
CNOT7
CREBBP
DEDD
EP300
ETV4
FANCL
HIPK1
HNRNPAB
HOXB13
MEIS1
PBX1
PBX4
RNPS1
RXRG
SNAI1
TIGD4
XRCC6
ZBTB32
ZMYND11
ZSCAN18
Entrez ID
2118
3233
HPRD ID
02833
00864
Ensembl ID
ENSG00000175832
ENSG00000170166
Uniprot IDs
P43268
P09016
PDB IDs
4CO8
4UUV
5ILU
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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