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EPS15 and ELF3
Data Source:
HPRD
(in vivo, two hybrid)
EPS15
ELF3
Description
epidermal growth factor receptor pathway substrate 15
E74 like ETS transcription factor 3
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Clathrin-coated Pit
Basal Plasma Membrane
Membrane
Aggresome
Apical Plasma Membrane
Clathrin Coat Of Coated Pit
Early Endosome Membrane
Intracellular Membrane-bounded Organelle
Postsynapse
Glutamatergic Synapse
Chromatin
Nucleus
Nucleoplasm
Golgi Apparatus
Cytosol
Molecular Function
Calcium Ion Binding
Protein Binding
SH3 Domain Binding
Polyubiquitin Modification-dependent Protein Binding
Cadherin Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Positive Regulation Of Receptor Recycling
Golgi To Endosome Transport
Endocytosis
Vesicle Organization
Endosomal Transport
Receptor-mediated Endocytosis Of Virus By Host Cell
Endocytic Recycling
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Viral Entry Into Host Cell
Clathrin Coat Assembly
Membrane Organization
Postsynaptic Neurotransmitter Receptor Internalization
Blastocyst Development
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Inflammatory Response
Cell Differentiation
Extracellular Matrix Organization
Epithelial Cell Differentiation
Positive Regulation Of Notch Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Mammary Gland Involution
Pathways
EGFR downregulation
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
InlB-mediated entry of Listeria monocytogenes into host cell
Pre-NOTCH Transcription and Translation
Drugs
Diseases
GWAS
Blood urea nitrogen levels (
31152163
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
IgE grass sensitization (
22036096
)
PR interval (
30046033
32439900
)
Interacting Genes
49 interacting genes:
AGFG1
AGFG2
AP1G1
AP2A1
AP2A2
CLINT1
CORO7
CRK
DNM1
DNM2
EGFR
ELF3
EPN1
EPN2
FCHO1
FCHO2
GRB2
HGS
ITSN1
LAPTM5
MAPK14
MOB4
MTNR1A
NAGPA
NEDD4
NUMB
NUMBL
PRKN
REPS2
RNF11
SCAMP1
SGIP1
SNAP91
SPART
SPOPL
STAM2
STAMBP
STON2
SYNJ1
TFAP2A
UBB
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2H
UBQLN1
USP8
15 interacting genes:
AR
CREBBP
EGFR
EP300
EPS15
JUN
MED23
MYC
NFKB1
PAK1
SOX9
TAF9
TBP
XRCC5
XRCC6
Entrez ID
2060
1999
HPRD ID
08968
03722
Ensembl ID
ENSG00000085832
ENSG00000163435
Uniprot IDs
B7Z240
P42566
A0A024R974
P78545
PDB IDs
1C07
1EH2
1F8H
1FF1
2IV9
2JXC
4RH5
4RH9
4RHG
4S0G
5AWT
5AWU
5JP2
2E8P
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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