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ENO1 and KDM2A
Data Source:
BioGRID
(two hybrid)
ENO1
KDM2A
Description
enolase 1
lysine demethylase 2A
Image
GO Annotations
Cellular Component
Phosphopyruvate Hydratase Complex
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Cell Surface
Membrane
M Band
Extracellular Exosome
Cell Cortex Region
Nucleoplasm
Molecular Function
Magnesium Ion Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
RNA Binding
Phosphopyruvate Hydratase Activity
Protein Binding
Protein Homodimerization Activity
Cadherin Binding
GTPase Binding
Transcription Coregulator Activity
Protein Binding
Zinc Ion Binding
Histone Demethylase Activity
Unmethylated CpG Binding
Histone Demethylase Activity (H3-K36 Specific)
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Gluconeogenesis
Glycolytic Process
Response To Virus
Positive Regulation Of Plasminogen Activation
Negative Regulation Of Cell Growth
Regulation Of Vacuole Fusion, Non-autophagic
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Muscle Contraction
Canonical Glycolysis
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of ATP Biosynthetic Process
Double-strand Break Repair Via Nonhomologous End Joining
Regulation Of Transcription By RNA Polymerase II
Protein Demethylation
Negative Regulation Of Transcription By Competitive Promoter Binding
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Histone H3-K36 Demethylation
Pathways
Glycolysis
Gluconeogenesis
Manipulation of host energy metabolism
HDMs demethylate histones
Drugs
Zinc
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Asthma (
30929738
)
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) (
23453885
)
Blood protein levels (
30072576
)
Feeling tense (
29500382
)
Platelet count (
32888494
)
Plateletcrit (
32888494
27863252
)
Tonsillectomy (
27182965
28928442
)
White blood cell count (
32888494
)
White blood cell count (basophil) (
27863252
)
Height (
28552196
28270201
)
Mean corpuscular volume (
27863252
)
Prostate cancer (
29892016
)
Red blood cell count (
32888494
27863252
)
Interacting Genes
59 interacting genes:
AGTPBP1
ALDOA
AMBP
ARID1B
BCL6
BHLHE40
BRCA1
CBX5
CHEK2
CLK1
COL14A1
CYSLTR2
DES
DUX4
FANCA
FHL1
FLNC
FYN
GLIS3
GRB2
HDAC1
HEMGN
HEY2
HK2
HSP90AB1
HSPA8
HSPB2
ITGB1
IVNS1ABP
KDM2A
LIG4
LINC01554
LONRF3
MCPH1
MED13
MYOC
NCOR1
P4HB
PAF1
PCNA
PLG
PPP2R5E
RXFP3
SERPING1
SET
SGCG
SNAPC3
SRC
SUMO2
SUMO4
TCAP
TEAD1
TERT
TRAPPC2
TTN
UPF2
YWHAQ
YWHAZ
ZBTB44
11 interacting genes:
ENO1
EP300
FBXO32
FOS
H3-4
H3C14
RELA
SMAD3
SMAD7
UBE2G2
ZNF512B
Entrez ID
2023
22992
HPRD ID
01400
05741
Ensembl ID
ENSG00000074800
ENSG00000173120
Uniprot IDs
A0A024R4F1
P06733
I3VM53
I3VM54
Q9Y2K7
PDB IDs
2PSN
3B97
5JLZ
5LAX
5NI9
5NIG
5OCK
2YU1
2YU2
4BBQ
6BYH
6C16
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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