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CTTN and ACTR3
Data Source:
HPRD
(in vitro, in vivo)
CTTN
ACTR3
Description
cortactin
actin related protein 3
Image
GO Annotations
Cellular Component
Ruffle
Podosome
Cytoplasm
Golgi Apparatus
Cytosol
Cytoskeleton
Actin Filament
Plasma Membrane
Clathrin-coated Pit
Focal Adhesion
Cell Cortex
Voltage-gated Potassium Channel Complex
Lamellipodium
Growth Cone
Site Of Polarized Growth
Cortical Cytoskeleton
Cortical Actin Cytoskeleton
Dendritic Spine
Intracellular Membrane-bounded Organelle
Mitotic Spindle Midzone
Nucleus
Cytoplasm
Cytosol
Arp2/3 Protein Complex
Brush Border
Cell-cell Junction
Focal Adhesion
Actin Cytoskeleton
Membrane
Lamellipodium
Site Of Double-strand Break
Extracellular Exosome
Molecular Function
Protein Binding
Profilin Binding
Cadherin Binding
Actin Filament Binding
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Actin Filament Binding
Biological Process
Intracellular Protein Transport
Receptor-mediated Endocytosis
Substrate-dependent Cell Migration, Cell Extension
Actin Filament Polymerization
Regulation Of Axon Extension
Regulation Of Actin Filament Polymerization
Positive Regulation Of Actin Filament Polymerization
Actin Cytoskeleton Reorganization
Positive Regulation Of Smooth Muscle Contraction
Focal Adhesion Assembly
Neuron Projection Morphogenesis
Cell Motility
Membrane Organization
Dendritic Spine Maintenance
Lamellipodium Organization
Regulation Of Autophagy Of Mitochondrion
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Establishment Or Maintenance Of Cell Polarity
Asymmetric Cell Division
Positive Regulation Of Lamellipodium Assembly
Meiotic Chromosome Movement Towards Spindle Pole
Meiotic Cytokinesis
Arp2/3 Complex-mediated Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Transcription By RNA Polymerase II
Ephrin Receptor Signaling Pathway
Spindle Localization
Cilium Assembly
Membrane Organization
Actin Polymerization-dependent Cell Motility
Cellular Response To Interferon-gamma
Pathways
RHO GTPases activate PAKs
Clathrin-mediated endocytosis
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
(2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Metabolite levels (
23823483
)
Systolic blood pressure in sickle cell anemia (
24058526
)
Interacting Genes
42 interacting genes:
ACD
ACTA1
ACTG1
ACTR3
ANKZF1
ARHGAP17
ARHGAP8
CASP3
CD2AP
CHD3
CTNND1
CTNND2
CTTNBP2
DNM1
DNM2
EGFR
FER
FGD1
GRB2
HAX1
HDAC6
HIP1R
KCNA2
KEAP1
MET
MYLK
NHSL2
RPL9
SDC3
SH3BP2
SHANK2
SIRT1
SMURF1
SPRR2A
SRC
SYK
TINF2
TJP1
TNK2
TRIM15
WASL
WIPF1
18 interacting genes:
ACTR2
ARPC2
ARPC3
ARPC4
ARPC5
CDC42
CDH1
CTTN
ERCC6
HCLS1
JUND
LINC01554
SHARPIN
UBE3A
WASF1
WASF2
WASF3
WASL
Entrez ID
2017
10096
HPRD ID
01268
05024
Ensembl ID
ENSG00000085733
ENSG00000115091
Uniprot IDs
A0A024R5M3
Q14247
Q53HG7
A0A024RAI1
B4DXW1
P61158
PDB IDs
1X69
2D1X
6UHC
6YW6
6YW7
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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