Wiki-Pi
About
Search
Browse
People
Updates
Search
AGTR2 and GNAI3
Data Source:
HPRD
(in vitro)
AGTR2
GNAI3
Description
angiotensin II receptor type 2
G protein subunit alpha i3
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Perinuclear Region Of Cytoplasm
Golgi Membrane
Cytoplasm
Lysosomal Membrane
Endoplasmic Reticulum Membrane
Centrosome
Heterotrimeric G-protein Complex
Plasma Membrane
Membrane
Midbody
Zymogen Granule
Membrane Raft
Extracellular Exosome
Molecular Function
G Protein-coupled Receptor Activity
Angiotensin Type II Receptor Activity
Protein Binding
Transcription Factor Binding
Receptor Antagonist Activity
G Protein-coupled Receptor Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein Domain Specific Binding
G-protein Beta/gamma-subunit Complex Binding
G Protein-coupled Serotonin Receptor Binding
GTPase Activating Protein Binding
Metal Ion Binding
Biological Process
Blood Vessel Remodeling
Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin
Renin-angiotensin Regulation Of Aldosterone Production
Cellular Sodium Ion Homeostasis
Inflammatory Response
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger
Nitric Oxide Mediated Signal Transduction
Brain Development
Regulation Of Blood Pressure
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Heart Rate
Negative Regulation Of Norepinephrine Secretion
Cerebellar Cortex Development
Negative Regulation Of Cell Growth
Negative Regulation Of Icosanoid Secretion
Positive Regulation Of Phosphoprotein Phosphatase Activity
Intracellular Signal Transduction
Positive Regulation Of Renal Sodium Excretion
Aldosterone Secretion
Angiotensin-activated Signaling Pathway
Regulation Of Protein Import Into Nucleus
Vasodilation
Dopamine Biosynthetic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Nitric Oxide Biosynthetic Process
Negative Regulation Of Fibroblast Proliferation
Positive Regulation Of Nitric-oxide Synthase Activity
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Kidney Morphogenesis
Cell Growth Involved In Cardiac Muscle Cell Development
Cellular Response To Dexamethasone Stimulus
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Negative Regulation Of Signaling Receptor Activity
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Protein Folding
Vesicle Fusion
Cell Cycle
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Dopamine Receptor Signaling Pathway
Brain Development
Positive Regulation Of Macroautophagy
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of NAD(P)H Oxidase Activity
GTP Metabolic Process
Cell Division
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Peptide ligand-binding receptors
G alpha (i) signalling events
PLC beta mediated events
PLC beta mediated events
Adenylate cyclase inhibitory pathway
Adenylate cyclase inhibitory pathway
G-protein activation
ADP signalling through P2Y purinoceptor 12
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Tasosartan
CYT006-AngQb
Diseases
Non-syndromic X-linked mental retardation
GWAS
Cystic fibrosis severity (
21602797
)
Gestational age at birth (maternal effect) (
28877031
)
Lung disease severity in cystic fibrosis (
26417704
)
Offspring birth weight (
31043758
)
Preterm birth (maternal effect) (
28877031
)
Type 2 diabetes (
29358691
30130595
)
Childhood body mass index (
33045005
)
Major depressive disorder (
20125088
)
Interacting Genes
11 interacting genes:
ACE
AGT
AGTRAP
ERBB3
ERBIN
GNAI2
GNAI3
MTUS1
PIK3CB
SNTA1
ZBTB16
43 interacting genes:
AGTR2
ATP12A
CCDC88A
CCDC88C
CCR5
CD48
CD59
CNR1
CXCR2
DRD2
GNB2
GNB4
GPSM1
GPSM2
GPSM3
HTR1A
LPAR1
MTNR1A
MTNR1B
NGB
NUCB1
NUCB2
PCP2
PHF24
PRKAR2B
PTPRU
RANGAP1
RGS10
RGS12
RGS14
RGS16
RGS17
RGS18
RGS19
RGS2
RGS20
RGS3
RGS5
RGS7
RIC8A
S1PR1
SOX30
TSHR
Entrez ID
186
2773
HPRD ID
02071
00765
Ensembl ID
ENSG00000180772
ENSG00000065135
Uniprot IDs
P50052
P08754
PDB IDs
5UNF
5UNG
5UNH
6JOD
2IHB
2ODE
2V4Z
4G5O
4G5R
4G5S
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?