Wiki-Pi
About
Search
Browse
People
Updates
Search
DUSP4 and LYSMD2
Data Source:
BioGRID
(two hybrid)
DUSP4
LYSMD2
Description
dual specificity phosphatase 4
LysM domain containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Tyrosine/threonine Phosphatase Activity
Phosphatase Activity
MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
Mitogen-activated Protein Kinase Binding
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
MAP Kinase Serine/threonine Phosphatase Activity
Biological Process
Inactivation Of MAPK Activity
Endoderm Formation
Protein Dephosphorylation
Dephosphorylation
Peptidyl-tyrosine Dephosphorylation
Peptidyl-threonine Dephosphorylation
Negative Regulation Of ERK1 And ERK2 Cascade
Pathways
RAF-independent MAPK1/3 activation
ERKs are inactivated
Negative regulation of MAPK pathway
Drugs
Diseases
GWAS
Gestational age at birth (maternal effect) (
28598419
)
Postoperative complication after cardiac surgery (
30678657
)
Response to statin therapy (
20339536
)
Spontaneous preterm birth (maternal effect) (
28598419
)
Interacting Genes
19 interacting genes:
APP
CRMP1
GORASP2
GRIN1
GRIN2D
LYSMD1
LYSMD2
LZTS2
MAPK1
MAPK14
MAPK3
MAPK8
MAPK9
NOXA1
PLEKHF2
TEPSIN
TRAF1
ZNF426
ZNF655
3 interacting genes:
CEP19
DUSP4
LCN9
Entrez ID
1846
256586
HPRD ID
04123
17531
Ensembl ID
ENSG00000120875
ENSG00000140280
Uniprot IDs
Q13115
Q8IV50
PDB IDs
3EZZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?