RCAN1 and ATP5PO

Data Source:
BioGRID (proximity labelling technology)

		RCAN1	ATP5PO
Description		regulator of calcineurin 1	ATP synthase peripheral stalk subunit OSCP
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Mitochondrial Proton-transporting ATP Synthase, Stator Stalk Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Plasma Membrane Proton-transporting ATP Synthase Complex, Catalytic Core F(1)
	Molecular Function	Nucleic Acid Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity	Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Calcium-mediated Signaling Calcineurin-NFAT Signaling Cascade Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Calcineurin-NFAT Signaling Cascade	ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Proton Transmembrane Transport
Pathways			Formation of ATP by chemiosmotic coupling Cristae formation
Drugs		Dipyridamole	Artenimol
Diseases
GWAS		Cancer ( 29299148) Rheumatoid arthritis ( 30423114 23143596 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes		8 interacting genes: APP BTRC GSK3B MAP3K3 MAPK3 PPP3CA USP22 UXT	19 interacting genes: APP CCDC136 CEP70 ERCC6 GOLGA2 HMBOX1 KRT13 KRT15 MIPOL1 NDC80 NME6 NT5C2 PNMA1 TEX13A TFIP11 TRIP6 USHBP1 ZBTB14 ZNF76
Entrez ID		1827	539
HPRD ID		04226	02899
Ensembl ID		ENSG00000159200	ENSG00000241837
Uniprot IDs		B7Z1F0 E9PDJ2 P53805 Q6FGP2 Q6ZMM3 V9GYW9	P48047
PDB IDs		6UUQ
Enriched GO Terms of Interacting Partners?
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