DSC1 and PKP3

Data Source:
HPRD (two hybrid)

		DSC1	PKP3
Description		desmocollin 1	plakophilin 3
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Plasma Membrane Cell-cell Junction Gap Junction Membrane Integral Component Of Membrane Desmosome Extracellular Exosome Ficolin-1-rich Granule Membrane	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Cell Junction Desmosome Messenger Ribonucleoprotein Complex
	Molecular Function	Calcium Ion Binding Protein Binding	RNA Binding Protein Binding Enzyme Binding Translation Regulator Activity Alpha-catenin Binding Cadherin Binding Cell Adhesion Molecule Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Keratinization Neutrophil Degranulation Cornification Cell-cell Adhesion	Desmosome Assembly Regulation Of Translation Cell-cell Junction Assembly Positive Regulation Of Gene Expression Keratinization Cornification Protein Localization To Plasma Membrane Cell-cell Adhesion Negative Regulation Of MRNA Catabolic Process
Pathways		Neutrophil degranulation Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Multiple sclerosis ( 23412934)	Anorectal malformation ( 31136621) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		8 interacting genes: DSG1 DSG2 DSP JUP PKP1 PKP2 PKP3 UCHL5	10 interacting genes: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP IQUB JUP KRT18
Entrez ID		1823	11187
HPRD ID		00511	05711
Ensembl ID		ENSG00000134765	ENSG00000184363
Uniprot IDs		Q08554 Q9HB00	Q9Y446
PDB IDs		5IRY
Enriched GO Terms of Interacting Partners?
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