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DYNC1LI2 and DMTN
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
DYNC1LI2
DMTN
Description
dynein cytoplasmic 1 light intermediate chain 2
dematin actin binding protein
Image
GO Annotations
Cellular Component
Kinetochore
Lysosome
Late Endosome
Centrosome
Cytosol
Cytoplasmic Dynein Complex
Microtubule
Membrane
Cytosol
Actin Filament
Plasma Membrane
Endomembrane System
Postsynaptic Density
Spectrin-associated Cytoskeleton
Actin Cytoskeleton
Cortical Cytoskeleton
Platelet Dense Tubular Network Membrane
Cell Projection Membrane
Cytoplasmic Vesicle
Perinuclear Region Of Cytoplasm
Molecular Function
Motor Activity
ATP Binding
Identical Protein Binding
Dynein Heavy Chain Binding
Actin Binding
Signaling Receptor Binding
Protein Binding
Spectrin Binding
Protein Self-association
Actin Filament Binding
Biological Process
Microtubule Cytoskeleton Organization
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Microtubule-based Movement
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Centrosome Localization
Cellular Response To Nerve Growth Factor Stimulus
Cytoskeleton Organization
Regulation Of Cell Shape
Regulation Of Lamellipodium Assembly
Positive Regulation Of Fibroblast Migration
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Cell-substrate Adhesion
Lamellipodium Assembly
Actin Cytoskeleton Organization
Positive Regulation Of Blood Coagulation
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of Peptidyl-serine Phosphorylation
Calcium-mediated Signaling Using Intracellular Calcium Source
Calcium-mediated Signaling Using Extracellular Calcium Source
Erythrocyte Development
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Actin Filament Bundle Assembly
Regulation Of Filopodium Assembly
Actin Filament Capping
Negative Regulation Of Focal Adhesion Assembly
Transmembrane Transport
Protein-containing Complex Assembly
Protein Secretion By Platelet
Cellular Response To Calcium Ion
Cellular Response To CAMP
Positive Regulation Of Wound Healing
Negative Regulation Of Protein Targeting To Membrane
Actin Filament Reorganization
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Platelet Aggregation
Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Miscellaneous transport and binding events
Drugs
Diseases
GWAS
Lipid traits (
30576415
)
Apolipoprotein B levels (
32203549
)
LDL cholesterol (
30275531
)
LDL cholesterol levels (
32203549
)
Low density lipoprotein cholesterol levels (
32154731
)
Total cholesterol levels (
30275531
)
Interacting Genes
4 interacting genes:
APP
BRCA2
DMTN
GAA
16 interacting genes:
ACTB
ACTC1
APP
CEP76
DYNC1LI2
EPB42
GOLGA2
NEDD4L
PRKACA
PROCR
PTOV1
SNCA
SNRPD2
SPTB
TEX11
TRAF2
Entrez ID
1783
2039
HPRD ID
09923
00506
Ensembl ID
ENSG00000135720
ENSG00000158856
Uniprot IDs
A0A024R6Z0
O43237
Q63HJ8
Q08495
PDB IDs
6F1T
6F1Y
6F38
6F3A
1QZP
1ZV6
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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