TIMM8A and STAM

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TIMM8A	STAM
Description		translocase of inner mitochondrial membrane 8A	signal transducing adaptor molecule
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space	Cytosol Early Endosome Membrane ESCRT-0 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	Nervous System Development Chaperone-mediated Protein Transport	Signal Transduction Endosomal Transport Macroautophagy Protein Deubiquitination Multivesicular Body Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly
Pathways		Mitochondrial protein import	EGFR downregulation Metalloprotease DUBs Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases		Mohr-Tranebjaerg syndrome
GWAS
Interacting Genes		8 interacting genes: ARID3A C1QTNF2 CAVIN3 KRT15 OIP5 STAM STAM2 TIMM13	20 interacting genes: ARRB1 HGS JAK1 JAK2 JAK3 MAP3K1 PJA1 PMEPA1 PPP1CA PPP1CC RFFL STAMBP TIMM8A TRIM54 TRIM55 TRIM63 UBC USP15 USP28 USP8
Entrez ID		1678	8027
HPRD ID		02287	03542
Ensembl ID		ENSG00000126953	ENSG00000136738
Uniprot IDs		A0A2R8YDA8 O60220	B4DZT2 Q92783
PDB IDs			2L0A 3F1I 3LDZ
Enriched GO Terms of Interacting Partners?
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