OXER1 and NEK8

Data Source:
BioGRID (two hybrid)

		OXER1	NEK8
Description		oxoeicosanoid receptor 1	NIMA related kinase 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Cytoplasm Centrosome Cilium Ciliary Inversin Compartment Ciliary Base
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway	Protein Phosphorylation Chromosome Segregation Determination Of Left/right Symmetry Heart Development Animal Organ Morphogenesis Regulation Of Hippo Signaling
Pathways		Eicosanoid ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases			Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Attention deficit hyperactivity disorder ( 18821565) Breastfeeding duration ( 25475840) Hyperactive-impulsive symptoms ( 18821565)	Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		46 interacting genes: ANAPC11 ARRB2 ASB13 ATG9A CCNK CRYBA2 EFCAB3 ESRP1 FOXH1 HNF1B HNRNPH1 INTS11 JMJD7 KRTAP12-3 KRTAP19-5 KRTAP4-2 KRTAP5-6 KRTAP6-3 LASP1 MED25 NCS1 NEK8 NOC4L OTX1 PLSCR4 PRKAB2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 RAMAC RBFOX2 RECK RNF208 RNF38 RNF44 TFG TLE5 TP53BP1 VGLL3 ZBTB32 ZC3H10 ZIC1	11 interacting genes: ACVR1 ADAMTSL4 KRTAP13-2 NEK9 OXER1 RGS20 TCF4 TGFBR1 TRIM42 TRIM69 UBC
Entrez ID		165140	284086
HPRD ID		17812	14822
Ensembl ID		ENSG00000162881	ENSG00000160602
Uniprot IDs		Q8TDS5	Q86SG6
PDB IDs
Enriched GO Terms of Interacting Partners?
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