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AP2B1 and C2CD6
Data Source:
BioGRID
(two hybrid)
AP2B1
C2CD6
Description
adaptor related protein complex 2 subunit beta 1
C2 calcium dependent domain containing 6
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Membrane
AP-2 Adaptor Complex
Clathrin Adaptor Complex
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Endolysosome Membrane
Clathrin-coated Endocytic Vesicle
Postsynapse
Glutamatergic Synapse
Molecular Function
Signal Sequence Binding
Protein Binding
Clathrin Binding
Clathrin Adaptor Activity
Protein-containing Complex Binding
Protein Binding
Biological Process
Kidney Development
Ventricular Septum Development
Intracellular Protein Transport
Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Low-density Lipoprotein Particle Receptor Catabolic Process
Low-density Lipoprotein Particle Clearance
Aorta Development
Positive Regulation Of Endocytosis
Ephrin Receptor Signaling Pathway
Clathrin Coat Assembly
Regulation Of Defense Response To Virus By Virus
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Coronary Vasculature Development
Membrane Organization
Clathrin-dependent Endocytosis
Postsynaptic Neurotransmitter Receptor Internalization
Negative Regulation Of Neuron Death
Positive Regulation Of Protein Localization To Membrane
Pathways
Nef Mediated CD4 Down-regulation
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Nef Mediated CD8 Down-regulation
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Chronotype (
30696823
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Immature fraction of reticulocytes (
32888494
)
Mean platelet volume (
22139419
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Platelet count (
22139419
27863252
)
Platelet distribution width (
27863252
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Interacting Genes
58 interacting genes:
ACVR1
AFF4
AP1M1
AP1M2
AP2A2
AP2M1
AP2S1
APC
ARRB1
ATM
ATP23
ATP6V1G1
BUB1
BUB1B
C2CD6
CCDC187
CLINT1
COL3A1
DHX58
DNAJC5
EGFR
FMNL2
GPANK1
GTF2I
HIP1
HSPB1
ITSN1
KANK2
KIAA0408
KPNA2
LDLRAP1
LONRF1
MEA1
MLH1
NECAP2
NEU4
NUP54
PIP5K1C
POM121
PSORS1C2
RAPGEF3
RIBC2
SLC25A6
SLC2A8
SMAD4
SMURF1
SNAP91
TENT5C
TERF2IP
TEX12
TGFBR1
TGFBR2
THAP1
TUBGCP4
TXN2
U2AF1
U2AF1L5
UBC
62 interacting genes:
ACOT11
ACTN3
ANKK1
AP2B1
BBS4
BHLHB9
BRCA1
CARD9
CCDC172
CCDC57
CCDC85B
CDR2
CHCHD3
CNOT11
CT55
DISC1
DNAJA3
FAM217B
FHL2
GOLGA2
GRAMD4
HAP1
HSF2BP
HSPB8
IKZF3
JRK
KIFC3
KRT13
KRT15
KRT31
KRT40
KRT75
LHX1
LHX3
LZTS2
MCM6
MCRS1
MEAF6
MEOX1
MIPOL1
MTUS2
NR5A1
NUTM1
PAX6
PIBF1
RNF8
SPATA2
TACC3
TCP10L
TEX11
TFIP11
TLE5
TRAF1
TRAF2
TRIM23
TRIM54
TSSK3
VAC14
VIM
VPS52
ZNF474
ZNRD2
Entrez ID
163
151254
HPRD ID
03015
08687
Ensembl ID
ENSG00000006125
ENSG00000155754
Uniprot IDs
A0A140VJE8
P63010
Q96EL6
A0A140VJE2
Q53TS8
PDB IDs
1E42
2G30
2IV8
2IV9
2JKR
2JKT
2VGL
2XA7
4UQI
5M5R
6QH5
6QH6
6QH7
6URI
6YAE
6YAF
6YAH
6YAI
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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