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TAMALIN and GRM2
Data Source:
HPRD
(two hybrid)
TAMALIN
GRM2
Description
trafficking regulator and scaffold protein tamalin
glutamate metabotropic receptor 2
Image
GO Annotations
Cellular Component
Plasma Membrane
Postsynaptic Density
Postsynaptic Membrane
Perinuclear Region Of Cytoplasm
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Plasma Membrane
Integral Component Of Plasma Membrane
Axon
Dendrite
Presynaptic Membrane
Astrocyte Projection
Integral Component Of Postsynaptic Membrane
Molecular Function
PDZ Domain Binding
Identical Protein Binding
Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity
Group II Metabotropic Glutamate Receptor Activity
G Protein-coupled Receptor Activity
Calcium Channel Regulator Activity
Protein Binding
Glutamate Receptor Activity
Scaffold Protein Binding
Biological Process
Signal Transduction
Protein Localization
Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway
G Protein-coupled Glutamate Receptor Signaling Pathway
Chemical Synaptic Transmission
Gene Expression
Glutamate Secretion
Regulation Of Protein Kinase B Signaling
Regulation Of Synaptic Transmission, Glutamatergic
Glutamate Homeostasis
Pathways
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
LY2140023
Diseases
GWAS
Interacting Genes
11 interacting genes:
CYTH3
DLG4
DOCK1
FYN
GABBR2
GRM1
GRM2
GRM3
GRM5
RPS6KA1
SRC
29 interacting genes:
ACBD5
AQP6
BIK
CCDC107
CLDN2
CLDN9
CPLX4
CYB5R3
GNA15
GNAQ
GRIP1
LMNA
MFSD14B
MGST3
MMGT1
NAALADL2
PDZK1IP1
RGS12
SAR1A
SDCBP
SLC30A8
SLC38A1
STOM
TAMALIN
TMEM130
TMEM237
TMEM248
TSPAN18
UBQLN1
Entrez ID
160622
2912
HPRD ID
17077
04977
Ensembl ID
ENSG00000161835
ENSG00000164082
Uniprot IDs
Q7Z6J2
Q14416
PDB IDs
2PNT
4XAQ
4XAS
5CNI
5CNJ
5KZN
5KZQ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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