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IQUB and ALX4
Data Source:
BioGRID
(two hybrid)
IQUB
ALX4
Description
IQ motif and ubiquitin domain containing
ALX homeobox 4
Image
GO Annotations
Cellular Component
Acrosomal Vesicle
Motile Cilium
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Molecular Function
Protein Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
HMG Box Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Smoothened Signaling Pathway
Cilium Assembly
Skeletal System Development
Hair Follicle Development
Regulation Of Transcription By RNA Polymerase II
Muscle Organ Development
Post-embryonic Development
Anterior/posterior Pattern Specification
Embryonic Forelimb Morphogenesis
Embryonic Hindlimb Morphogenesis
Embryonic Digit Morphogenesis
Regulation Of Apoptotic Process
Positive Regulation Of Transcription By RNA Polymerase II
Digestive Tract Development
Embryonic Skeletal System Morphogenesis
Roof Of Mouth Development
Pathways
Drugs
Diseases
Frontonasal dysplasia
Enlarged parietal foramina/cranium bifidum
GWAS
Blood pressure measurement (high sodium intervention) (
24165912
)
Brain morphology (MOSTest) (
32665545
)
Cadmium levels (
26025379
)
Excessive hairiness (
29895819
)
Gout (
22179738
)
Male-pattern baldness (
29146897
27182965
)
Monobrow (
27182965
)
Response to antidepressants in depression (
29998114
)
Thrombin-activatable fibrinolysis inhibitor activation peptide (
29378355
)
Interacting Genes
57 interacting genes:
ALX4
ANAPC11
ANKRD23
BHLHB9
BLZF1
CALCOCO2
CEP70
CEP76
CYSRT1
DIP2A
DYNLL1
EYA2
FAM107A
GOLGA2
IHO1
KATNAL1
KIFC3
KRT40
KRT75
KRT76
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP12-2
KRTAP12-4
LHX3
MAGEA6
MDFI
PATZ1
PIH1D2
PIK3R3
PKP3
POU6F2
PRDM6
PRR23D1
PRR23D2
RHOH
SAXO1
SMN1
SMN2
SORBS3
SYCE1
TMCC2
TP53BP2
TRAF2
TRAF6
TRIM23
TRIM27
TRIM42
TRIM50
TRIM54
TRIM55
TRIM63
ZNF143
ZNF410
ZNF526
ZRANB1
14 interacting genes:
ALX1
CEBPE
EMX1
FOXA3
GATA4
HOXA3
HOXB13
HOXB6
HOXD3
IQUB
LEF1
PARVG
SOX10
SOX2
Entrez ID
154865
60529
HPRD ID
08194
05661
Ensembl ID
ENSG00000164675
ENSG00000052850
Uniprot IDs
A0A024R771
Q8NA54
Q9H161
PDB IDs
2DAF
2M0C
Enriched GO Terms of Interacting Partners
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