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ADRA2B and GGA3
Data Source:
BioGRID
(affinity chromatography technology, pull down)
ADRA2B
GGA3
Description
adrenoceptor alpha 2B
golgi associated, gamma adaptin ear containing, ARF binding protein 3
Image
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Intracellular Membrane-bounded Organelle
Lysosome
Golgi Apparatus
Trans-Golgi Network
Endosome Membrane
Early Endosome Membrane
Protein-containing Complex
Recycling Endosome Membrane
Molecular Function
G Protein-coupled Receptor Activity
Alpha2-adrenergic Receptor Activity
Protein Binding
Epinephrine Binding
Protein Binding
Small GTPase Binding
Ubiquitin Binding
Protein-containing Complex Binding
Biological Process
Activation Of MAPK Activity
Regulation Of Vascular Associated Smooth Muscle Contraction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Female Pregnancy
Negative Regulation Of Norepinephrine Secretion
Platelet Activation
Activation Of Protein Kinase B Activity
Negative Regulation Of Epinephrine Secretion
Receptor Transactivation
Positive Regulation Of MAPK Cascade
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Blood Pressure
Positive Regulation Of Uterine Smooth Muscle Contraction
Adrenergic Receptor Signaling Pathway
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Protein Targeting To Lysosome
Intracellular Protein Transport
Regulation Of Protein Stability
Protein Destabilization
Endocytic Recycling
Protein Localization To Cell Surface
Golgi To Plasma Membrane Protein Transport
Cellular Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Amyloid-beta Formation
Pathways
Adrenoceptors
Adrenaline signalling through Alpha-2 adrenergic receptor
G alpha (i) signalling events
G alpha (z) signalling events
TBC/RABGAPs
MET receptor recycling
Amyloid fiber formation
Drugs
Amphetamine
Tramadol
Bethanidine
Ziprasidone
Cabergoline
Ropinirole
Etomidate
Clozapine
Norepinephrine
Phenylpropanolamine
Loxapine
Prochlorperazine
Prazosin
Chlorpromazine
Brimonidine
Haloperidol
Nortriptyline
Amoxapine
Clonidine
Lisuride
Guanabenz
Epinephrine
Tizanidine
Apomorphine
Paroxetine
Trimipramine
Risperidone
Tolazoline
Fenoldopam
Phenoxybenzamine
Maprotiline
Oxymetazoline
Apraclonidine
Guanfacine
Ergoloid mesylate
Promethazine
Carvedilol
Desipramine
Escitalopram
Pergolide
Bromocriptine
Quetiapine
Aripiprazole
Paliperidone
Ephedra sinica root
Mephentermine
Yohimbine
Methotrimeprazine
Dextroamphetamine
Metamfetamine
Celiprolol
Dronedarone
Rotigotine
OPC-28326
Epicept NP-1
Mianserin
Pizotifen
Asenapine
Ocaperidone
Droxidopa
Esmirtazapine
Xylometazoline
Levonordefrin
Dosulepin
Etoperidone
Lorpiprazole
Cirazoline
Moxisylyte
Aranidipine
Setiptiline
Racepinephrine
Dihydroergocornine
DL-Methylephedrine
Xylazine
Indigotindisulfonic acid
Tiapride
Dihydroergocristine
Aripiprazole lauroxil
Diseases
GWAS
Monocyte percentage of white cells (
32888494
)
Interacting Genes
8 interacting genes:
EIF2B1
GGA1
GGA2
GGA3
GNAI2
PPP1R9B
UCHL1
YWHAZ
38 interacting genes:
ADRA2A
ADRA2B
AFTPH
AP1S2
ARAP3
ARF1
ARF3
CDKN2A
CLINT1
CLTC
CYTH2
DAZAP2
EGFR
GGA1
GGA2
IGF2R
LITAF
LRP10
M6PR
P4HA3
PACS1
PLEKHB2
RABEP1
RNF11
RNF214
RPS27A
STAB1
SYNRG
TBC1D3
TOLLIP
TRAPPC6A
TRIM23
TSG101
UBC
UPRT
VPS11
VPS18
ZNF497
Entrez ID
151
23163
HPRD ID
00086
10443
Ensembl ID
ENSG00000274286
ENSG00000125447
Uniprot IDs
P18089
A8K6M0
B7Z456
Q9NZ52
PDB IDs
2CVA
6K41
6K42
1JPL
1JUQ
1LF8
1P4U
1WR6
1YD8
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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