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CTRL and CLDN5
Data Source:
BioGRID
(two hybrid)
CTRL
CLDN5
Description
chymotrypsin like
claudin 5
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Integral Component Of Membrane
Apicolateral Plasma Membrane
Cell Junction
Cortical Actin Cytoskeleton
Tight Junction
Molecular Function
Serine-type Endopeptidase Activity
Protein Binding
Serine-type Peptidase Activity
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Biological Process
Proteolysis
Protein Catabolic Process
Outflow Tract Morphogenesis
Cell-cell Junction Assembly
Cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Learning
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Positive Regulation Of Protein Binding
Maintenance Of Blood-brain Barrier
Negative Regulation Of Vascular Permeability
Roof Of Mouth Development
Face Morphogenesis
Bicellular Tight Junction Assembly
Tight Junction Assembly
Positive Regulation Of Establishment Of Endothelial Barrier
Positive Regulation Of Bicellular Tight Junction Assembly
Establishment Of Blood-retinal Barrier
Regulation Of Bicellular Tight Junction Assembly
Pathways
Tight junction interactions
RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
4 interacting genes:
CLDN5
FAM209A
FATE1
SERPINA3
40 interacting genes:
AQP1
BTNL8
CCDC167
CLDN3
CLRN2
CNPY3
CORIN
CTRL
CXCL9
CYB561A3
EFNA5
EHHADH
ERG28
ERMP1
FXYD6-FXYD2
GYPA
LAT
LHFPL5
MIP
MPDZ
PLP2
PLPPR2
PMP22
RPRM
SFTPC
SGCG
SLC35B4
SMIM3
TECR
TF
TJP1
TMEM128
TMEM140
TMEM14C
TMEM182
TMEM190
TMEM222
TSPAN2
VAMP5
YIPF1
Entrez ID
1506
7122
HPRD ID
00344
03654
Ensembl ID
ENSG00000141086
ENSG00000184113
Uniprot IDs
A0A024R6Z5
P40313
D3DX19
O00501
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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