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HSCB and BBS2
Data Source:
BioGRID
(two hybrid)
HSCB
BBS2
Description
HscB mitochondrial iron-sulfur cluster cochaperone
Bardet-Biedl syndrome 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytosol
Microvillus
Membrane
Motile Cilium
Stereocilium
BBSome
Ciliary Basal Body
Neuron Projection
Ciliary Membrane
Molecular Function
ATPase Activator Activity
Molecular_function
Protein Binding
Identical Protein Binding
Metal Ion Binding
Chaperone Binding
RNA Polymerase II Repressing Transcription Factor Binding
Protein Binding
Biological Process
Iron-sulfur Cluster Assembly
Positive Regulation Of ATPase Activity
[2Fe-2S] Cluster Assembly
Protein Complex Oligomerization
Protein Maturation By Iron-sulfur Cluster Transfer
Sperm Axoneme Assembly
Visual Perception
Protein Localization
Negative Regulation Of Gene Expression
Artery Smooth Muscle Contraction
Striatum Development
Hippocampus Development
Cerebral Cortex Development
Adult Behavior
Melanosome Transport
Protein Localization To Organelle
Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway
Negative Regulation Of Multicellular Organism Growth
Positive Regulation Of Multicellular Organism Growth
Vasodilation
Golgi To Plasma Membrane Protein Transport
Fat Cell Differentiation
Photoreceptor Cell Maintenance
Brain Morphogenesis
Cartilage Development
Cilium Assembly
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Non-motile Cilium Assembly
Pathways
Mitochondrial protein import
Mitochondrial protein import
Mitochondrial iron-sulfur cluster biogenesis
BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
Bardet-Biedl syndrome (BBS)
GWAS
Breast size (
27182965
)
Diastolic blood pressure (
27841878
)
Esophageal cancer and gastric cancer (
20729852
)
Mean platelet volume (
32888494
)
Myeloproliferative neoplasms (
33057200
)
Pancreatic cancer (
25086665
)
Red cell distribution width (
27863252
)
Systolic blood pressure (
27841878
)
Interacting Genes
4 interacting genes:
AGTRAP
BBS1
BBS2
BBS4
15 interacting genes:
BHMT
EEF1A1
EPAS1
EXOC7
FHOD1
FNDC3B
HNRNPF
HSCB
KRT18
LMO4
MDFI
NRF1
PAX2
PSME3
RBPMS
Entrez ID
150274
583
HPRD ID
16289
05855
Ensembl ID
ENSG00000100209
ENSG00000125124
Uniprot IDs
A0A384NYJ4
B0QYH2
Q8IWL3
Q9BXC9
PDB IDs
3BVO
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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