MOB3C and LATS2

Data Source:
BioGRID (pull down)

		MOB3C	LATS2
Description		MOB kinase activator 3C	large tumor suppressor kinase 2
Image		No pdb structure
GO Annotations	Cellular Component		Spindle Pole Nucleus Cytosol Centriolar Satellite
	Molecular Function	Protein Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process		G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Hormone-mediated Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-serine Phosphorylation Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Organ Growth Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Localization To Nucleus
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Chronic kidney disease ( 30226566) Hypertension ( 30226566)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Refractive error ( 32231278)
Interacting Genes		18 interacting genes: APP CMTM3 FAM118A FBXO7 IKZF4 KANK2 KRT40 LATS1 LATS2 NT5C2 PCYT1A PICK1 PTPN21 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10	67 interacting genes: ABL1 AJUBA AKT1 ARAF ARNT AURKA AURKB BECN1 BRAF CBLC CCND2 CCNE1 CD44 CDK2 CDK4 CDK6 CDKN1A CDKN2A CDKN2B CDKN2C CHEK1 CHEK2 CTNNB1 DYRK1A EPHA2 ERBB2 EZH2 FGFR4 FHL3 FZR1 GLIS1 GLIS2 GRAP2 GRM1 HGF HIF1A KAT2A KDELR2 KIF23 MAP2K3 MAP2K5 MAPK14 MDM4 MET MOB3A MOB3B MOB3C MOB4 MYC NF2 NFIC PDGFRA RAF1 RASSF1 RELA SMAD2 SNAI1 STK11 STK3 SUZ12 TAZ TEAD2 TP53 TSC1 WWTR1 YWHAG YWHAZ
Entrez ID		148932	26524
HPRD ID		17584	07277
Ensembl ID		ENSG00000142961	ENSG00000150457
Uniprot IDs		Q70IA8 X6R3L3	A0A024RDM3 Q9NRM7
PDB IDs			4ZRI
Enriched GO Terms of Interacting Partners?
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