RAD9B and HUS1

Data Source:
HPRD (in vivo)

		RAD9B	HUS1
Description		RAD9 checkpoint clamp component B	HUS1 checkpoint clamp component
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Checkpoint Clamp Complex	Nucleus Nucleoplasm Nucleolus Cytosol Checkpoint Clamp Complex Site Of Double-strand Break
	Molecular Function	Protein Binding 3'-5' Exonuclease Activity	Protein Binding
	Biological Process	DNA Replication Checkpoint DNA Replication DNA Repair Intra-S DNA Damage Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Signal Transduction By P53 Class Mediator	DNA Damage Checkpoint Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Regulation Of Protein Phosphorylation DNA Replication DNA Repair Nucleotide-excision Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Response To UV Embryo Development Ending In Birth Or Egg Hatching Intra-S DNA Damage Checkpoint Mitotic DNA Replication Checkpoint Meiotic DNA Integrity Checkpoint Cellular Response To Ionizing Radiation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint	Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS			Gut microbiota alpha diversity (Shannon index) ( 33208821) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507)
Interacting Genes		5 interacting genes: HUS1 HUS1B RAD1 RAD17 RAD9A	28 interacting genes: C4orf46 CD200 DCUN1D5 DNAJC7 FEN1 GRIP1 HDAC1 HUS1B MSH2 MSH3 MSH6 NEIL1 NTAQ1 OGG1 PCNA POLB RAD1 RAD17 RAD9A RAD9B RHNO1 RPA1 RPA2 SDCBP SIRT6 TDG TOPBP1 YWHAQ
Entrez ID		144715	3364
HPRD ID		12221	04787
Ensembl ID		ENSG00000151164	ENSG00000136273
Uniprot IDs		A0A024RBJ5 A0A024RBN9 B4DX60 B4DYM6 J3KPN7 Q6WBX8	A4D2F2 O60921
PDB IDs			3A1J 3G65 3GGR 6J8Y
Enriched GO Terms of Interacting Partners?
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