CWF19L2 and TRIM23

Data Source:
BioGRID (two hybrid)

		CWF19L2	TRIM23
Description		CWF19 like cell cycle control factor 2	tripartite motif containing 23
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GO Annotations	Cellular Component	Post-mRNA Release Spliceosomal Complex	Golgi Membrane Nucleus Cytoplasm Lysosomal Membrane Plasma Membrane
	Molecular Function	Protein Binding	GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding GDP Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Intracellular Protein Transport Viral Process Vesicle-mediated Transport Protein Ubiquitination Innate Immune Response Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Coronary artery disease ( 29212778) Cortex volume ( 31530798) Diastolic blood pressure ( 27841878) Fourth ventricle volume ( 31530798) Parkinson's disease progression (cognitive) ( 33111402) Pars opercularis volume ( 31530798) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		80 interacting genes: ABLIM3 APP AXIN2 BACH2 BRCA1 CALCOCO1 CALCOCO2 CARD10 CARD9 CCDC102B CCDC136 CCDC57 CCDC88B CEP63 CEP70 CEP76 CFAP53 CNTROB CWF19L1 DES DISC1 EXOC8 FAM9B FCHO1 FSD2 FXR1 FXR2 GAS8 GFAP GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOOK1 HOOK2 HSF2BP IKBKG IKZF1 KANK2 KASH5 KIF24 KIFC3 KRT40 LHX3 LHX9 LIMS1 LMNA LZTS1 LZTS2 M1AP MAD1L1 MEOX1 MTUS2 NAB2 NDEL1 PDE4DIP PIBF1 PICK1 PSTPIP1 RINT1 SF3B4 SNW1 STX11 TAX1BP1 TBC1D1 TFIP11 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM37 TRIM54 TRIM9 VIM VPS52 ZBTB8A ZMYND12 ZNF35 ZNF655 ZRANB1	218 interacting genes: ACTN4 AKTIP ANKRD36BP1 ANKRD55 AP3M1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 BAZ2B BICRAL BRME1 C2CD6 C8orf33 CARD9 CBX8 CCDC13 CCDC146 CCDC25 CCDC33 CDC20B CDC73 CDR2 CFAP53 CHP1P2 COX5B CPNE7 CREB5 CSRP2 CWF19L2 CXCL14 CYTH1 CYTH2 DCX DEPP1 DMC1 DMRT3 DNAAF4 DOCK2 EAF2 EHHADH EIF3D ENKD1 EPN2 EXOC3-AS1 FAM110A FAM133A FAM193B FAM83A FAM90A1 FBF1 FHIT FLAD1 FXR2 GAD1 GATA2 GCC2-AS1 GEM GGA2 GGA3 GLIDR GMCL2 GPANK1 GPKOW HAPLN2 HAUS1 HGS HNRNPLL HOXB5 HSPB7 IL16 IQCE IQUB JOSD1 JRK KAT5 KIFC3 KLHL42 KRT6A KRT75 KRT76 LAGE3 LENG1 LGALS14 LGALS3 LGALS8 LINC00526 LINC01018 LMO2 LMO3 LNX1 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MSRB3 MTFR2 MYEF2 MYOM1 MYOZ1 NAB2 NEDD9 NEK6 NFU1 NOXA1 NTAQ1 NUDT21 NXT2 PDE4D PHF1 PIAS2 PIK3R2 PITX1 PKP4 PLEKHA2 POLI POLL POM121 PPIL2 PPP1R15B PPP1R18 PRPF18 PRPF31 PSMA1 PSMB1 RAD18 RAMAC RCAN3 RIBC1 RIBC2 RIN1 RNF126 RNF213 RNF32 RNF34 RNF6 RSRC2 RTP5 RUFY1 SCNM1 SF1 SH2D4A SIAH1 SIRPA SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SNRPB2 SNW1 SORBS3 SPG21 STK19 SUMO1P1 TACO1 TASOR2 TBC1D22B TCEA2 TCEANC TEPSIN TEX33 TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TRIM55 TRIM63 TROAP TSEN54 TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2I UBE2L3 UBE2N UBE2U UBE2W UBOX5 UBQLN1 USP2 USP20 USP21 UTP23 VGLL1 WDR25 ZBTB16 ZBTB4 ZC2HC1C ZFAND2A ZNF20 ZNF250 ZNF408 ZNF417 ZNF474 ZNF564 ZNF581 ZNF587 ZNF688 ZNF835
Entrez ID		143884	373
HPRD ID		13102	03449
Ensembl ID		ENSG00000152404	ENSG00000113595
Uniprot IDs		Q2TBE0	P36406
PDB IDs		6ID0 6ID1	5VZV 5VZW
Enriched GO Terms of Interacting Partners?
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